Ly-GDI/RhoGDI2/ARHGDIB Antibody (E-7): sc-374525
- Ly-GDI/RhoGDI2/ARHGDIB Antibody (E-7) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 159-189 near the C-terminus of Ly-GDI of human origin
- recommended for detection of Ly-GDI of mouse, rat, human and origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- See Ly-GDI/RhoGDI2/ARHGDIB (G-12): sc-376473 for Ly-GDI/RhoGDI2/ARHGDIB antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for Ly-GDI/RhoGDI2/ARHGDIB Antibody (E-7) for WB applications. This reagent is now offered in a bundle with Ly-GDI/RhoGDI2/ARHGDIB Antibody (E-7) (see ordering information below).
QUICK LINKS
SEE ALSO...
Ly-GDI Antibody (E-7) is a mouse monoclonal IgG2a antibody that detects Ly-GDI in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Ly-GDI, also known as Rho GDIβ, plays a crucial role in regulating the activity of Rho family GTPases, which are essential for various cellular processes, including cell migration, adhesion, and cytoskeletal dynamics. By binding to these GTPases, Ly-GDI inhibits their activation, thereby preventing inappropriate signaling that could lead to uncontrolled cell proliferation or migration. This regulatory function is particularly important in hematopoietic cells, where Ly-GDI is predominantly expressed in B and T lymphocyte cell lines, influencing immune responses and maintaining cellular homeostasis. The interaction of Ly-GDI with Rho GTPases is vital for the proper functioning of the immune system, as Ly-GDI helps to modulate the signaling pathways that govern lymphocyte activation and differentiation. Anti-Ly-GDI antibody (E-7) serves as an invaluable tool for researchers studying the intricate signaling networks that underpin cellular behavior in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ly-GDI/RhoGDI2/ARHGDIB Antibody (E-7) | sc-374525 | 200 µg/ml | $322.00 | |||
Ly-GDI/RhoGDI2/ARHGDIB Antibody (E-7): m-IgG Fc BP-HRP Bundle | sc-540466 | 200 µg Ab; 10 µg BP | $361.00 | |||
Ly-GDI/RhoGDI2/ARHGDIB (E-7) Neutralizing Peptide | sc-374525 P | 100 µg/0.5 ml | $69.00 |