LTβR Antibody (6D66): sc-71518
- LTβR Antibody (6D66) is a rat monoclonal IgG1 provided at 50 µg/0.5 ml
- raised against amino acids 28-220 of LTβR of human origin
- recommended for detection of LTβR of human origin by IP and FCM
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for LTβR Antibody (6D66). This work is in progress.
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SEE ALSO...
LTβR Antibody (6D66) is a rat monoclonal IgG1 antibody that detects LTβR in human samples through immunoprecipitation (IP) and flow cytometry (FCM) applications. LTβR, or lymphotoxin β receptor, plays a crucial role in the immune system by mediating the development and organization of lymphoid tissues, which are essential for effective immune responses. LTβR is primarily located on the surface of various cell types, excluding T and B lymphocytes, and LTβR activation is vital for the signaling pathways that lead to the activation of NFκB, a key transcription factor involved in regulating immune responses and cell survival. The interaction of LTβR with its ligand, the heterotrimeric lymphotoxin LT-α1/β2, triggers a cascade of events that not only promotes lymphoid organ development but also influences the apoptosis of certain cell types, highlighting LTβR importance in maintaining immune homeostasis. Anti-LTβR antibody (6D66) is an invaluable tool for researchers studying the complexities of immune system regulation and the development of lymphoid structures, providing insights into potential therapeutic targets for immune-related diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LTβR Antibody (6D66) | sc-71518 | 50 µg/0.5 ml | $316.00 |