LOC728109 Antibody (G-2): sc-515290

LOC728109 Antibody (G-2) is a mouse monoclonal IgM kappa antibody that detects LOC728109 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). LOC728109 (G-2) antibody is available as the non-conjugated form. LOC728109 protein is located on chromosome 20, which harbors various genes crucial for reproductive health, particularly in the epididymis, where proteins are essential for sperm maturation and function. Expression of these genes in the epididymis is vital for seminal production, and researchers are exploring them as potential targets for male contraception, highlighting their importance in fertility regulation. Additionally, chromosome 20 is associated with several critical health conditions, including prion diseases such as Creutzfeldt-Jakob disease, as well as amyotrophic lateral sclerosis and Alagille syndrome, underscoring LOC728109′s relevance in both reproductive biology and broader health implications.

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LOC728109 Antibody (G-2) References:

1. Does PRNP gene control the clinical and pathological phenotype of human spongiform transmissible encephalopathies?  |  Masullo, C. and Macchi, G. 2001. Clin Neuropathol. 20: 19-25. PMID: 11220690
2. Gerstmann-Sträussler-Scheinker syndrome,fatal familial insomnia, and kuru: a review of these less common human transmissible spongiform encephalopathies.  |  Collins, S., et al. 2001. J Clin Neurosci. 8: 387-97. PMID: 11535002
3. Early pattern of epilepsy in the ring chromosome 20 syndrome.  |  Ville, D., et al. 2006. Epilepsia. 47: 543-9. PMID: 16529619
4. Trisomy 20 mosaicism and nonmosaic trisomy 20: a report of 2 cases.  |  Joó, JG., et al. 2006. J Reprod Med. 51: 209-12. PMID: 16674019
5. Eppin: an epididymal protease inhibitor and a target for male contraception.  |  O'Rand, MG., et al. 2007. Soc Reprod Fertil Suppl. 63: 445-53. PMID: 17566290
6. A locus on chromosome 20 encompassing genes that are highly expressed in the epididymis.  |  Lundwall, A. 2007. Asian J Androl. 9: 540-4. PMID: 17589793
7. Ring chromosome 20 syndrome without deletions of the subtelomeric and CHRNA4--KCNQ2 genes loci.  |  Elghezal, H., et al. 2007. Eur J Med Genet. 50: 441-5. PMID: 17851150
8. Cellular pathways leading to neuronal dysfunction and degeneration.  |  Kazantsev, AG. 2007. Drug News Perspect. 20: 501-9. PMID: 18080037
9. Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.  |  Gao, P., et al. 2013. Cell. 153: 1094-107. PMID: 23647843
10. G2Retro as a two-step graph generative models for retrosynthesis prediction.  |  Chen, Z., et al. 2023. Commun Chem. 6: 102. PMID: 37253928
11. G2BFNN: Generalized geodesic basis function neural network.  |  Zhao, Y., et al. 2024. Neural Netw. 180: 106701. PMID: 39288642
12. The prion diseases.  |  Prusiner, SB. 1998. Brain Pathol. 8: 499-513. PMID: 9669700

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-LOC728109 Antibody (G-2) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-LOC728109 Antibody (G-2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

LOC728109 Antibody (G-2) Specifications

Alternate Product Name: LOC728109

Product Clone Name: G-2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 126-144

Epitope Target: LOC728109

Epitope Species: human

Product Reactivity/Detection: LOC728109

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for LOC728109 Antibody (G-2): P: Blocking Peptide