Lipocalin-1 Antibody (H-8): sc-374620
- Lipocalin-1 Antibody (H-8) is a mouse monoclonal IgG2b κ Lipocalin-1 antibody, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 41-85 mapping within an internal region of Lipocalin-1 of human origin
- Lipocalin-1 Antibody (H-8) is recommended for detection of Lipocalin-1 of human origin by WB, IP, IF and ELISA
- Anti-Lipocalin-1 Antibody (H-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2b BP-HRP is the preferred secondary detection reagent for Lipocalin-1 Antibody (H-8) for WB applications. This reagent is now offered in a bundle with Lipocalin-1 Antibody (H-8) (see ordering information below).
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Lipocalin-1 Antibody (H-8) is a mouse monoclonal IgG2b kappa light chain antibody that detects Lipocalin-1 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Lipocalin-1 antibody (H-8) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Lipocalin-1, also known as tear lipocalin or von Ebner′s gland protein, is a secretory protein predominantly found in fluids that cover epithelial surfaces, such as tears and respiratory secretions. Lipocalin-1 plays a crucial role in stabilizing the lipid film of human tear fluid by effectively removing harmful lipids from the corneal surface and transporting them to the aqueous phase of tears, which is vital for maintaining ocular health and comfort. Lipocalin-1 is secreted by various glands, including the lacrimal, lingual, nasal mucosal, tracheobronchial, sweat, mammary, adrenal, prostate, thymus, testis, and corticotrophs of the pituitary gland, highlighting its widespread importance in different physiological processes. Lipocalin-1′s ability to bind and transport hydrophobic molecules, such as bitter substances on the tongue, further emphasizes its multifaceted role in human biology.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Lipocalin-1 Antibody (H-8) References:
- Molecular cloning of a novel lipocalin-1 interacting human cell membrane receptor using phage display. | Wojnar, P., et al. 2001. J Biol Chem. 276: 20206-12. PMID: 11287427
- Presence of tear lipocalin and other major proteins in lacrimal fluid of rabbits. | Azzarolo, AM., et al. 2004. Comp Biochem Physiol B Biochem Mol Biol. 138: 111-7. PMID: 15193265
- Human tear lipocalin exhibits antimicrobial activity by scavenging microbial siderophores. | Fluckinger, M., et al. 2004. Antimicrob Agents Chemother. 48: 3367-72. PMID: 15328098
- The 1.8-A crystal structure of human tear lipocalin reveals an extended branched cavity with capacity for multiple ligands. | Breustedt, DA., et al. 2005. J Biol Chem. 280: 484-93. PMID: 15489503
- Tear lipocalin: evidence for a scavenging function to remove lipids from the human corneal surface. | Gasymov, OK., et al. 2005. Invest Ophthalmol Vis Sci. 46: 3589-96. PMID: 16186338
- Possible role for salivary gland protein in taste reception indicated by homology to lipophilic-ligand carrier proteins. | Schmale, H., et al. 1990. Nature. 343: 366-9. PMID: 1689010
- EP-GP and the lipocalin VEGh, two different human salivary 20-kDa proteins. | Schenkels, LC., et al. 1995. J Dent Res. 74: 1543-50. PMID: 7560414
- Molecular cloning of human von Ebner's gland protein, a member of the lipocalin superfamily highly expressed in lingual salivary glands. | Bläker, M., et al. 1993. Biochim Biophys Acta. 1172: 131-7. PMID: 7679926
- Denatonium bitter tasting among transgenic mice expressing rat von Ebner's gland protein. | Kock, K., et al. 1994. Physiol Behav. 56: 1173-7. PMID: 7878087
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Lipocalin-1 Antibody (H-8) | sc-374620 | 200 µg/ml | $322.00 | |||
Lipocalin-1 Antibody (H-8): m-IgG2b BP-HRP Bundle | sc-548748 | 200 µg Ab; 10 µg BP | $361.00 | |||
Lipocalin-1 Antibody (H-8) AC | sc-374620 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Lipocalin-1 Antibody (H-8) HRP | sc-374620 HRP | 200 µg/ml | $322.00 | |||
Lipocalin-1 Antibody (H-8) FITC | sc-374620 FITC | 200 µg/ml | $336.00 | |||
Lipocalin-1 Antibody (H-8) PE | sc-374620 PE | 200 µg/ml | $349.00 | |||
Lipocalin-1 Antibody (H-8) Alexa Fluor® 488 | sc-374620 AF488 | 200 µg/ml | $364.00 | |||
Lipocalin-1 Antibody (H-8) Alexa Fluor® 546 | sc-374620 AF546 | 200 µg/ml | $364.00 | |||
Lipocalin-1 Antibody (H-8) Alexa Fluor® 594 | sc-374620 AF594 | 200 µg/ml | $364.00 | |||
Lipocalin-1 Antibody (H-8) Alexa Fluor® 647 | sc-374620 AF647 | 200 µg/ml | $364.00 | |||
Lipocalin-1 Antibody (H-8) Alexa Fluor® 680 | sc-374620 AF680 | 200 µg/ml | $364.00 | |||
Lipocalin-1 Antibody (H-8) Alexa Fluor® 790 | sc-374620 AF790 | 200 µg/ml | $364.00 |