Lck Antibody (28): sc-135971
- Lck Antibody (28) is a mouse monoclonal IgG1, cited in 1 publications, provided at 50 µg/0.5 ml
- raised against amino acids 1-191 of Lck of human origin
- recommended for detection of Lck of mouse, rat and human origin by WB, IP and IF; not recommended for IP
- See Lck (3A5): sc-433 for Lck antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Lck Antibody (28). This work is in progress.
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SEE ALSO...
Lck Antibody (28) is a mouse monoclonal IgG1 antibody that detects Lck in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Lck is a crucial member of the Src family of non-receptor tyrosine kinases, which play a vital role in T cell signaling and immune response regulation. Specifically, Lck is predominantly located in the plasma membrane of T cells, where Lck is essential for initiating T cell receptor (TCR) signaling upon antigen recognition. This localization is critical because Lck phosphorylates key substrates, thereby propagating the signaling cascade that leads to T cell activation, proliferation, and differentiation. Proper functioning of Lck is paramount for effective immune responses, and dysregulation of Lck activity can lead to various immunological disorders, including autoimmune diseases and lymphomas. Anti-Lck antibody (28) provides reliable detection of Lck, facilitating research into Lck′s role in T cell biology and implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Lck Antibody (28) | sc-135971 | 50 µg/0.5 ml | $322.00 |