Lamin A Antibody (133A2): sc-56137
- Lamin A Antibody (133A2) is a mouse monoclonal IgG3, cited in 20 publications, provided at 50 µg/0.5 ml
- raised against partially purified recombinant Lamin A protein of human origin
- recommended for detection of Lamin A of mouse, rat and human origin by WB, IF and FCM; also reactive with additional species, including and bovine and canine; non cross-reactive with Lamin C
- See Lamin A/C (E-1): sc-376248 for Lamin A antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Lamin A Antibody (133A2). This work is in progress.
Lamin A Antibody (133A2) is a mouse monoclonal IgG3 antibody designed to specifically detect the human Lamin A protein, also known as LMNA or A-type lamin. Lamin A is essential for maintaining the structural integrity of the nuclear envelope, which is crucial for preserving cellular morphology and ensuring proper nuclear function. Lamin A plays a vital role in regulating key cellular processes such as DNA replication, transcription, and cell cycle progression, making Lamin A indispensable for cellular longevity and stability. Anti-Lamin A antibody (133A2) is raised against a partially purified recombinant human Lamin A protein. Lamin A monoclonal antibody (133A2) is capable of detecting Lamin A in multiple species, including mouse, rat, human, bovine, and canine, across various applications such as western blotting (WB), immunofluorescence (IF), and flow cytometry (FCM). Importantly, Lamin A (133A2) antibody does not cross-react with Lamin C, a splice variant of Lamin A, ensuring precise targeting in experiments. The ability to accurately identify Lamin A is critical for research into nuclear structure, gene expression regulation, and the investigation of laminopathies, which are a group of diseases caused by defects in the LMNA gene. By providing reliable and consistent results, anti-Lamin A antibody (133A2) serves as an essential tool for both basic and applied biomedical research, facilitating advancements in our understanding of cellular mechanics and related pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Lamin A Antibody (133A2) | sc-56137 | 50 µg/0.5 ml | $322.00 |