LACC1 Antibody (H-6): sc-376064
- LACC1 Antibody (H-6) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 251-283 within an internal region of LACC1 of human origin
- recommended for detection of LACC1 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for LACC1 Antibody (H-6) for WB applications. These reagents are now offered in bundles with LACC1 Antibody (H-6) (see ordering information below).
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SEE ALSO...
LACC1 Antibody (H-6) is a mouse monoclonal IgG1 antibody that detects LACC1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). LACC1, a 430 amino acid protein encoded by a gene located on chromosome 13, plays a significant role in various cellular processes, including the regulation of cell proliferation and apoptosis. Anti-LACC1 antibody (H-6) has potential involvement in tumor suppression research, as chromosome 13 harbors key tumor suppressor genes like BRCA2 and RB1, which are critical for maintaining genomic stability and preventing malignant transformations. LACC1 monoclonal antibody (H-6) helps study expression patterns that may provide insights into functional roles in both normal physiology and disease states. Understanding LACC1′s interactions and regulatory mechanisms could pave the way for novel therapeutic strategies in cancer treatment and other related disorders.
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LACC1 Antibody (H-6) References:
- Association of a mutation in LACC1 with a monogenic form of systemic juvenile idiopathic arthritis. | Wakil, SM., et al. 2015. Arthritis Rheumatol. 67: 288-95. PMID: 25220867
- Functional Analyses of the Crohn's Disease Risk Gene LACC1. | Assadi, G., et al. 2016. PLoS One. 11: e0168276. PMID: 27959965
- LACC1 Gene Defects in Familial Form of Juvenile Arthritis. | Karacan, I., et al. 2018. J Rheumatol. 45: 726-728. PMID: 29717096
- LACC1 gene mutation in three sisters with polyarthritis without systemic features. | Singh, A., et al. 2020. Ann Rheum Dis. 79: 425-426. PMID: 31811059
- LACC1 Required for NOD2-Induced, ER Stress-Mediated Innate Immune Outcomes in Human Macrophages and LACC1 Risk Variants Modulate These Outcomes. | Huang, C., et al. 2019. Cell Rep. 29: 4525-4539.e4. PMID: 31875558
- A novel loss-of-function mutation in LACC1 underlies hereditary juvenile arthritis with extended intra-familial phenotypic heterogeneity. | Butbul Aviel, Y., et al. 2021. Rheumatology (Oxford). 60: 4888-4898. PMID: 33493343
- LACC1-associated JIA linked to autophagy defects in macrophages. | Clarke, J. 2021. Nat Rev Rheumatol. 17: 251. PMID: 33762710
- MicroRNA-211-5p in extracellular vesicles derived from BMSCs facilitates the repair of rat frozen shoulder via regulating KDM2B/LACC1 axis. | Mao, X., et al. 2023. Tissue Cell. 81: 102006. PMID: 36610229
- LACC1 Promoted Nerve Injury in an Anesthesia-Induced Cognitive Disorder Model via RIP2 Expression through ROS-NOD2 Induction. | Lu, K., et al. 2024. Altern Ther Health Med. 30: 202-207. PMID: 38064597
- BBOX1, LACC1, MMP7 and SSTR1 as common predictors in obesity and non-alcoholic fatty liver disease. | Huang, C., et al. 2025. Genes Dis. 12: 101310. PMID: 39619480
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LACC1 Antibody (H-6) | sc-376064 | 200 µg/ml | $322.00 | |||
LACC1 Antibody (H-6): m-IgG Fc BP-HRP Bundle | sc-537962 | 200 µg Ab; 10 µg BP | $361.00 | |||
LACC1 Antibody (H-6): m-IgGκ BP-HRP Bundle | sc-535456 | 200 µg Ab; 40 µg BP | $361.00 | |||
LACC1 Antibody (H-6): m-IgG1 BP-HRP Bundle | sc-545470 | 200 µg Ab; 20 µg BP | $361.00 | |||
LACC1 (H-6) Neutralizing Peptide | sc-376064 P | 100 µg/0.5 ml | $69.00 |