Date published: 2025-10-2

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L-Histidine monohydrochloride monohydrate (CAS 5934-29-2)

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Alternate Names:
(2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid hydrate hydrochloride
Application:
L-Histidine monohydrochloride monohydrate is a histamine precursor via histidine decarboxylase
CAS Number:
5934-29-2
Purity:
≥98%
Molecular Weight:
209.63
Molecular Formula:
C6H9N3O2•HCl•H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-Histidine monohydrochloride monohydrate is an amino acid derivative that plays a role in the synthesis of proteins. It is involved in the formation of histamine. L-Histidine monohydrochloride monohydrate is a precursor for the synthesis of hemoglobin, a protein that carries oxygen in the blood. It acts as a metal chelator, binding to metal ions and facilitating their transport and storage. L-Histidine monohydrochloride monohydrate is an important component of many enzymes and is involved in various metabolic pathways. L-Histidine monohydrochloride monohydrate is a precursor for the synthesis of other biologically active molecules, such as carnosine and anserine, which have antioxidant and anti-inflammatory properties. L-Histidine monohydrochloride monohydrate is a molecule for various biochemical processes.


L-Histidine monohydrochloride monohydrate (CAS 5934-29-2) References

  1. Physical state of L-histidine after freeze-drying and long-term storage.  |  Osterberg, T. and Wadsten, T. 1999. Eur J Pharm Sci. 8: 301-8. PMID: 10425380
  2. Physical properties of a silicone prosthetic elastomer stored in simulated skin secretions.  |  Polyzois, GL., et al. 2000. J Prosthet Dent. 83: 572-7. PMID: 10793391
  3. Poly(L-histidine)-PEG block copolymer micelles and pH-induced destabilization.  |  Lee, ES., et al. 2003. J Control Release. 90: 363-74. PMID: 12880703
  4. Structure orientation of hemin self-assembly layer determining the direct electron transfer reaction.  |  Wang, GX., et al. 2015. Chem Commun (Camb). 51: 689-92. PMID: 25418674
  5. A comparative study of the low-frequency vibrations of l-histidine molecule in different solid states.  |  Xu, L., et al. 2020. Spectrochim Acta A Mol Biomol Spectrosc. 224: 117468. PMID: 31425861
  6. Classification and mitigation of negative injection experiences with biologic medications.  |  Fernandez, JM., et al. 2020. Dermatol Ther. 33: e13240. PMID: 32012405
  7. Safety and efficacy of l-histidine monohydrochloride monohydrate produced using Corynebacterium glutamicum KCCM 80172 for all animal species.  |  , ., et al. 2019. EFSA J. 17: e05783. PMID: 32626390
  8. Safety and efficacy of l-histidine monohydrochloride monohydrate produced using Corynebacterium glutamicum KCCM 80179 for all animal species.  |  , ., et al. 2019. EFSA J. 17: e05784. PMID: 32626391
  9. Safety and efficacy of l-histidine monohydrochloride monohydrate produced by fermentation with Escherichia coli (NITE BP-02526) for all animal species.  |  , ., et al. 2019. EFSA J. 17: e05785. PMID: 32626407
  10. Assessment of the application for renewal of authorisation of l-histidine monohydrochloride monohydrate produced with Escherichia coli NITE SD 00268 for salmonids and its extension of use to other fin fish.  |  , ., et al. 2020. EFSA J. 18: e06072. PMID: 32874284
  11. Fast remote correlation experiments for 1H homonuclear decoupling in solids.  |  Moutzouri, P., et al. 2020. J Magn Reson. 321: 106856. PMID: 33157355
  12. Safety and Efficacy of l-histidine monohydrochloride monohydrate produced by fermentation using Escherichia coli KCCM 80212 as a feed additive for all animal species.  |  , ., et al. 2020. EFSA J. 18: e06287. PMID: 33204314
  13. Safety and efficacy of a feed additive consisting of l-histidine monohydrochloride monohydrate produced using Escherichia coli  NITE SD 00268 for all animal species (Kyowa Hakko Europe GmbH).  |  , ., et al. 2021. EFSA J. 19: e06622. PMID: 34093782

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-Histidine monohydrochloride monohydrate, 5 g

sc-263442
5 g
$20.00

L-Histidine monohydrochloride monohydrate, 25 g

sc-263442A
25 g
$23.00

L-Histidine monohydrochloride monohydrate, 250 g

sc-263442B
250 g
$92.00

L-Histidine monohydrochloride monohydrate, 1 kg

sc-263442C
1 kg
$337.00