KVβ Antibody (H-5): sc-398362
- KVβ Antibody (H-5) is a mouse monoclonal IgA κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 232-249 within an internal region of KVβ.2 of human origin
- recommended for detection of KVβ.1 and KVβ.2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- m-IgGκ BP-HRP is the preferred secondary detection reagent for KVβ Antibody (H-5) for WB applications. This reagent is now offered in a bundle with KVβ Antibody (H-5) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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KVβ Antibody (H-5) is a mouse monoclonal IgA antibody that detects KVβ in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). KVβ, also known as KCNAB2, KKvβ2.1, or AKR6A5, plays a crucial role as an accessory subunit in the assembly of voltage-gated potassium channels, which are essential for regulating the excitability of neurons and muscle cells. These channels are vital for the repolarization phase of action potentials, ensuring proper signaling and communication within the nervous system and muscle tissues. KVβ subunits, including KVβ.2, interact with the pore-forming alpha subunits of the KV channel family, influencing their gating properties and surface expression. This interaction allows for the fine-tuning of channel activity, which is critical for maintaining cellular homeostasis and responding to physiological stimuli. The precise regulation of KVβ subunits is essential for the formation of functional neuronal channels, highlighting their significance in both health and disease. Anti-KVβ antibody (H-5) is an invaluable tool for researchers studying the dynamics of potassium channel function and their implications in various biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KVβ Antibody (H-5) | sc-398362 | 200 µg/ml | $322.00 | |||
KVβ Antibody (H-5): m-IgGκ BP-HRP Bundle | sc-552170 | 200 µg Ab; 40 µg BP | $361.00 | |||
KVβ (H-5) Neutralizing Peptide | sc-398362 P | 100 µg/0.5 ml | $69.00 |