KLHDC4 Antibody (D-10): sc-398672

KLHDC4 Antibody (D-10) is a mouse monoclonal IgG1 antibody that detects KLHDC4 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). KLHDC4, or kelch domain-containing protein 4, is a 520 amino acid protein characterized by the presence of six kelch repeats and exists in three alternatively spliced isoforms, which may play distinct roles in cellular processes. KLHDC4 is primarily located in the cytoplasm, where KLHDC4 is believed to be involved in various signaling pathways and cellular functions, including the regulation of actin cytoskeleton dynamics and protein degradation. This localization is crucial as KLHDC4 interacts with other cytoplasmic proteins, thereby influencing cellular responses to stress and maintaining cellular homeostasis. The gene encoding KLHDC4 is situated on human chromosome 16q24.2, a region associated with several genetic disorders, including Crohn′s disease and Rubinstein-Taybi syndrome, highlighting KLHDC4′s importance in both normal physiology and disease states. With versatile applications and significant role in cellular function, anti-KLHDC4 antibody (D-10) is an essential tool for researchers studying the molecular mechanisms underlying various biological processes and diseases.

The preferred KLHDC4 antibody is KLHDC4 Antibody (H-9): sc-398467.