Kinectin 1 Antibody (G-5): sc-374576
- Kinectin 1 Antibody (G-5) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 1156-1345 mapping near the C-terminus of Kinectin 1 of human origin
- recommended for detection of Kinectin 1 isoforms 1 and 2 of human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for Kinectin 1 Antibody (G-5) for WB and IHC(P) applications. These reagents are now offered in bundles with Kinectin 1 Antibody (G-5) (see ordering information below).
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Kinectin 1 Antibody (G-5) is a mouse monoclonal IgG2a antibody that detects Kinectin 1 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Kinectin 1, also known as the kinesin receptor, is an integral membrane protein located in the endoplasmic reticulum (ER) and plays a crucial role in the transport of vesicles along microtubules, which is essential for maintaining cellular organization and function. The interaction between Kinectin 1 and kinesin motor proteins facilitates the movement of cargo within cells, ensuring essential materials reach appropriate destinations. This transport mechanism is vital for processes such as neurotransmitter release in neurons and organelle distribution, which are critical for cell survival and function. Proper functioning of Kinectin 1 is important not only for intracellular transport but also for overall cellular health, making Kinectin 1 a significant target for research in cellular biology and neurobiology.
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LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Kinectin 1 Antibody (G-5) References:
- Significant, replicable, and functional associations between KTN1 variants and alcohol and drug codependence. | Luo, X., et al. 2021. Addict Biol. 26: e12888. PMID: 32115811
- Rab18 regulates focal adhesion dynamics by interacting with kinectin-1 at the endoplasmic reticulum. | Guadagno, NA., et al. 2020. J Cell Biol. 219: PMID: 32525992
- lncRNA KTN1‑AS1 promotes glioma cell proliferation and invasion by negatively regulating miR‑505‑3p. | Mu, Y., et al. 2020. Oncol Rep. 44: 2645-2655. PMID: 33125151
- Kinectin 1 promotes the growth of triple-negative breast cancer via directly co-activating NF-kappaB/p65 and enhancing its transcriptional activity. | Gao, L., et al. 2021. Signal Transduct Target Ther. 6: 250. PMID: 34219129
- Upregulating KTN1 promotes Hepatocellular Carcinoma progression. | Pan, J., et al. 2021. J Cancer. 12: 4791-4809. PMID: 34234850
- Human microRNA-182-5p and kinectin 1: Potential biomarkers for prognosis in oral squamous cell carcinoma. | Jakob, M., et al. 2021. Head Neck. 43: 3707-3719. PMID: 34591354
- Sex-different interrelationships of rs945270, cerebral gray matter volumes, and attention deficit hyperactivity disorder: a region-wide study across brain. | Luo, X., et al. 2022. Transl Psychiatry. 12: 225. PMID: 35654767
- A significant, functional and replicable risk KTN1 variant block for schizophrenia. | Mao, Q., et al. 2023. Sci Rep. 13: 3890. PMID: 36890161
- LncRNA KTN1-AS1 facilitates esophageal squamous cell carcinoma progression via miR-885-5p/STRN3 axis. | Chen, L., et al. 2024. Genes Genomics. 46: 241-252. PMID: 37747640
- Pan-cancer analysis combined with experimental validation revealed that KTN1 is an immunological and prognostic biomarker. | Ouyang, Y., et al. 2024. Transl Cancer Res. 13: 5830-5844. PMID: 39697730
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Kinectin 1 Antibody (G-5) | sc-374576 | 200 µg/ml | $322.00 | |||
Kinectin 1 Antibody (G-5): m-IgG Fc BP-HRP Bundle | sc-540478 | 200 µg Ab; 10 µg BP | $361.00 | |||
Kinectin 1 Antibody (G-5): m-IgG2a BP-HRP Bundle | sc-546912 | 200 µg Ab; 10 µg BP | $361.00 |