KIF3C Antibody (B-10): sc-393778
- KIF3C Antibody (B-10) is a mouse monoclonal IgG1 κ KIF3C antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 764-795 near the C-terminus of KIF3C of human origin
- KIF3C Antibody (B-10) is recommended for detection of KIF3C of human origin by WB, IP, IF and ELISA
- Anti-KIF3C Antibody (B-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for KIF3C Antibody (B-10) for WB applications. These reagents are now offered in bundles with KIF3C Antibody (B-10) (see ordering information below).
KIF3C Antibody (B-10) is a mouse monoclonal IgG1 kappa light chain antibody that detects KIF3C protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-KIF3C antibody (B-10) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. KIF3C is a member of the kinesin family, which comprises a diverse group of microtubule-dependent motor proteins essential for intracellular transport. KIF3C plays a pivotal role in the anterograde transport of membrane-bound organelles, particularly in neurons, where KIF3C facilitates the movement of vesicles and protein complexes necessary for the proper functioning of cilia and flagella. KIF3C is primarily localized in the cytoplasm and is crucial for maintaining cellular organization and function, especially during neuronal development. Notably, KIF3C is highly expressed in neural tissues such as the brain, spinal cord, and retina, and KIF3C expression is upregulated during neuroblastoma differentiation, indicating a significant role in neuronal maturation and potential implications in neurodevelopmental disorders. The human KIF3C gene is located on chromosome 2p23 and encodes a 793 amino acid protein, underscoring KIF3C′s importance in both cellular transport mechanisms and the overall health of the nervous system.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
KIF3C Antibody (B-10) References:
- Molecular motors and their role in membrane traffic. | Hamm-Alvarez, SF. 1998. Adv Drug Deliv Rev. 29: 229-242. PMID: 10837592
- Molecular cloning and functional analysis of mouse C-terminal kinesin motor KifC3. | Yang, Z., et al. 2001. Mol Cell Biol. 21: 765-70. PMID: 11154264
- Stirring up development with the heterotrimeric kinesin KIF3. | Hirokawa, N. 2000. Traffic. 1: 29-34. PMID: 11208056
- Kinesin-II, the heteromeric kinesin. | Cole, DG. 1999. Cell Mol Life Sci. 56: 217-26. PMID: 11212349
- Expression of KIF3C kinesin during neural development and in vitro neuronal differentiation. | Navone, F., et al. 2001. J Neurochem. 77: 741-53. PMID: 11331403
- Functional analysis of mouse kinesin motor Kif3C. | Yang, Z., et al. 2001. Mol Cell Biol. 21: 5306-11. PMID: 11463814
- cDNA cloning, genomic organization, and chromosomal localization of a novel human gene that encodes a kinesin-related protein highly similar to mouse Kif3C. | Telford, EA., et al. 1998. Biochem Biophys Res Commun. 242: 407-12. PMID: 9446808
- Characterization of the KIF3C neural kinesin-like motor from mouse. | Yang, Z. and Goldstein, LS. 1998. Mol Biol Cell. 9: 249-61. PMID: 9450952
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KIF3C Antibody (B-10) | sc-393778 | 200 µg/ml | $316.00 | |||
KIF3C Antibody (B-10): m-IgG Fc BP-HRP Bundle | sc-530577 | 200 µg Ab; 10 µg BP | $354.00 | |||
KIF3C Antibody (B-10): m-IgGκ BP-HRP Bundle | sc-524085 | 200 µg Ab, 40 µg BP | $354.00 | |||
KIF3C Antibody (B-10): m-IgG1 BP-HRP Bundle | sc-544141 | 200 µg Ab; 20 µg BP | $354.00 | |||
KIF3C Antibody (B-10) AC | sc-393778 AC | 500 µg/ml, 25% agarose | $416.00 | |||
KIF3C Antibody (B-10) HRP | sc-393778 HRP | 200 µg/ml | $316.00 | |||
KIF3C Antibody (B-10) FITC | sc-393778 FITC | 200 µg/ml | $330.00 | |||
KIF3C Antibody (B-10) PE | sc-393778 PE | 200 µg/ml | $343.00 | |||
KIF3C Antibody (B-10) Alexa Fluor® 488 | sc-393778 AF488 | 200 µg/ml | $357.00 | |||
KIF3C Antibody (B-10) Alexa Fluor® 546 | sc-393778 AF546 | 200 µg/ml | $357.00 | |||
KIF3C Antibody (B-10) Alexa Fluor® 594 | sc-393778 AF594 | 200 µg/ml | $357.00 | |||
KIF3C Antibody (B-10) Alexa Fluor® 647 | sc-393778 AF647 | 200 µg/ml | $357.00 | |||
KIF3C Antibody (B-10) Alexa Fluor® 680 | sc-393778 AF680 | 200 µg/ml | $357.00 | |||
KIF3C Antibody (B-10) Alexa Fluor® 790 | sc-393778 AF790 | 200 µg/ml | $357.00 | |||
KIF3C (B-10) Neutralizing Peptide | sc-393778 P | 100 µg/0.5 ml | $68.00 |