KIAA1191 Antibody (G-4): sc-398723

KIAA1191 Antibody (G-4) is a mouse monoclonal IgM antibody that detects KIAA1191 in human, mouse, and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-KIAA1191 antibody (G-4) is available as a non-conjugated format. KIAA1191 is a 305 amino acid protein that belongs to the UPF0498 family and exists in three alternatively spliced isoforms, which may have distinct functions and regulatory mechanisms. The gene encoding KIAA1191 spans approximately 15,908 bases and is located on human chromosome 5q35.2, a region comprising nearly 6% of the human genome and associated with various genetic disorders. KIAA1191 plays a crucial role in cellular processes, including RNA metabolism and gene expression regulation, which are vital for maintaining cellular homeostasis and responding to environmental changes. Understanding KIAA1191 function is important, as dysregulation may contribute to the development of diseases, including certain cancers and genetic syndromes. KIAA1191′s interactions with other cellular proteins further underscore significance in complex biological pathways, making KIAA1191 (G-4) monoclonal antibody an essential tool for researchers investigating these critical processes.

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KIAA1191 Antibody (G-4) References:

1. Familial adenomatous polyposis and mental retardation caused by a de novo chromosomal deletion at 5q15-q22: report of a case.  |  Finch, R., et al. 2005. Dis Colon Rectum. 48: 2148-52. PMID: 16228830
2. Damage-induced ubiquitylation of human RNA polymerase II by the ubiquitin ligase Nedd4, but not Cockayne syndrome proteins or BRCA1.  |  Anindya, R., et al. 2007. Mol Cell. 28: 386-97. PMID: 17996703
3. Haematological & molecular profile of acute myelogenous leukaemia in India.  |  Sazawal, S., et al. 2009. Indian J Med Res. 129: 256-61. PMID: 19491417
4. Superior outcome with hypomethylating therapy in patients with acute myeloid leukemia and high-risk myelodysplastic syndrome and chromosome 5 and 7 abnormalities.  |  Ravandi, F., et al. 2009. Cancer. 115: 5746-51. PMID: 19795507
5. Characterization of a de novo complex chromosomal rearrangement in a patient with cri-du-chat and trisomy 5p syndromes.  |  Vera-Carbonell, A., et al. 2009. Am J Med Genet A. 149A: 2513-21. PMID: 19842199
6. Characterizing the novel protein p33MONOX.  |  Mishra, M., et al. 2011. Mol Cell Biochem. 350: 127-34. PMID: 21153684
7. Brain-Derived Neurotrophic Factor in Neonatal Seizures.  |  Sullivan, BJ. and Kadam, SD. 2021. Pediatr Neurol. 118: 35-39. PMID: 33773288
8. The role of KIAA1191 in the necroptotic pathway of multiple myeloma.  |  Xu, Z., et al. 2022. Ann Hematol. 101: 359-367. PMID: 34989828
9. Serum biomarkers in patients with drug-resistant epilepsy: a proteomics-based analysis.  |  Ma, M., et al. 2024. Front Neurol. 15: 1383023. PMID: 38585359
10. The mutational spectrum in Treacher Collins syndrome reveals a predominance of mutations that create a premature-termination codon.  |  Edwards, SJ., et al. 1997. Am J Hum Genet. 60: 515-24. PMID: 9042910
11. Human and murine PTX1/Ptx1 gene maps to the region for Treacher Collins syndrome.  |  Crawford, MJ., et al. 1997. Mamm Genome. 8: 841-5. PMID: 9337397
12. Confirmation of homozygosity for a single nucleotide substitution mutation in a Cockayne syndrome patient using monoallelic mutation analysis in somatic cell hybrids.  |  McDaniel, LD., et al. 1997. Hum Mutat. 10: 317-21. PMID: 9338586

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-KIAA1191 Antibody (G-4) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-KIAA1191 Antibody (G-4) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

KIAA1191 Antibody (G-4) Specifications

Alternate Product Name: KIAA1191

Product Clone Name: G-4

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 209-246

Epitope Target: KIAA1191

Epitope Species: human

Product Reactivity/Detection: KIAA1191 of human origin, 4833439L19Rik of mouse origin and the corresponding rat homolog

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for KIAA1191 Antibody (G-4): P: Blocking Peptide