KCNMB4 Antibody (E-5): sc-515713

KCNMB4 Antibody (E-5) is a mouse monoclonal IgG2a antibody that detects KCNMB4 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). KCNMB4, also known as Slo-beta-4 or Maxi K channel subunit beta-4, is a 210 amino acid multi-pass membrane protein that plays a crucial role as a regulatory subunit of the calcium-activated potassium MaxiKα channel. KCNMB4 is predominantly expressed in the brain, where KCNMB4 significantly contributes to the diversity of MaxiKα channels by modulating their calcium sensitivity and gating kinetics. KCNMB4′s ability to coassemble with MaxiKα subunits enhances the functional complexity of these channels, which are essential for maintaining smooth muscle tone and neuronal excitability. Understanding the interactions and regulatory mechanisms involving KCNMB4 is vital for elucidating KCNMB4′s role in various physiological processes and potential pathophysiological conditions, making anti-KCNMB4 antibody (E-5) an invaluable tool for researchers studying these critical pathways.

The preferred KCNMB4 antibody is KCNMB4 Antibody (B-6): sc-515712.