Anti-KAT I Antibody (C-7) is a mouse monoclonal IgG1 (kappa light chain) KAT I antibody provided at 200 µg/ml
specific for an epitope mapping between amino acids 6-29 at the N-terminus of KAT I of human origin
Anti-KAT I Antibody (C-7) is recommended for detection of KAT I isoforms 1, 2 and 3 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine
Anti-KAT I Antibody (C-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of KAT I (C-7): sc-374531.
m-IgG Fc BP-HRP is the preferred secondary detection reagent for KAT I Antibody (C-7) for WB and IHC(P) applications. This reagent is now offered in a bundle with KAT I Antibody (C-7) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
KAT I Antibody (C-7) is a high quality monoclonal KAT I antibody (also designated KAT I antibody) suitable for the detection of the KAT I protein of mouse, rat and human origin. KAT I Antibody (C-7) is available as both the non-conjugated anti-KAT I antibody form, as well as multiple conjugated forms of anti-KAT I antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Kynurenine aminotransferases KAT I, KAT II, and KAT III belong to the class-I pyridoxal-phosphate-dependent aminotransferase family. KAT I is a cytoplasmic protein involved in glutamine catabolism. KAT I functions in the catalysis of the transamination of L-kinurenine to form kynurenic acid, a neuroprotective and anticonvulsant metabolite of tryptophan. Kynurenic acid is involved in synaptic transmission and has been implicated in a number of neurological disorders including schizophrenia and Huntington′s disease. KAT I also functions in the metabolism of cysteine conjugates in some halogenated alkenes and alkanes to form reactive metabolites. KAT I has three isoforms. Isoform 1is the full length protein, isoform 2 lacks amino acids 68-117 and isoform 3 lacks amino acids 251-422. Based on sequence similarity, KAT I is thought to function as a homodimer.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences