karyopherin 13 Antibody (B-8): sc-271751

karyopherin 13 Antibody (B-8) is a mouse monoclonal IgG3 antibody that detects karyopherin 13 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Karyopherin 13, also known as Importin-13 or Ran-binding protein 13, is a crucial nuclear transport receptor composed of 963 amino acids, featuring twenty HEAT repeats and one importin N-terminal domain. Karyopherin 13 plays a vital role in nuclear import and export processes, facilitating the transport of essential cargo substrates such as UBC9, the RBM8A/MAGOH complex, Pax-6, eIF1AY, and Ran, which are integral to various cellular functions including gene expression regulation and cell cycle progression. Karyopherin 13′s localization in both the nucleus and cytoplasm underscores its importance in maintaining cellular homeostasis and responding to cellular signals. The gene encoding karyopherin 13 is mapped to human chromosome 1p34.1 and mouse chromosome 4 D2.1, highlighting its evolutionary conservation and significance across species. With its ability to interact with a range of proteins, karyopherin 13 is essential for proper functioning of cellular transport mechanisms, making anti-karyopherin 13 antibody (B-8) an invaluable tool for researchers studying nuclear transport and related pathways.

The preferred karyopherin 13 antibody is karyopherin 13 Antibody (D-3): sc-271218.