


KAP3 Antibody (14) is a mouse monoclonal IgG1 antibody that detects KAP3 in mouse, rat, human, and canine samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). KAP3, also known as SMAP (Small G protein GDP dissociation stimulator-associated protein), plays a crucial role as an adaptor protein that facilitates the interaction between kinesin superfamily proteins and chromosome-associated proteins, which is essential for proper chromosome movement during cell division. KAP3′s ability to form ternary complexes with human chromosome-associated polypeptide (HCAP) and kinesin II proteins, KIF3A and KIF3B, underscores KAP3′s importance in maintaining chromosomal stability and ensuring accurate segregation during mitosis. Additionally, KAP3 is a substrate for tyrosine phosphorylation by v-Src, which may influence KAP3′s function and interactions within the cell. The presence of KAP3 in various species highlights KAP3′s evolutionary conservation and significance in cellular processes, making anti-KAP3 antibody (14) a valuable tool for researchers studying chromosomal dynamics and motor protein interactions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KAP3 Antibody (14) | sc-135958 | 50 µg/500 µl | $322.00 |