JYL-1433 CAS: 565448-40-0
MF: C26H36N3FO4S2
MW: 537.7
A selective transient receptor potential TRPV1 antagonist..

JYL-1433 (CAS 565448-40-0)

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Application: A selective transient receptor potential TRPV1 antagonist.
CAS Number: 565448-40-0
Molecular Weight: 537.7
Molecular Formula: C26H36N3FO4S2
* Refer to Certificate of Analysis for lot specific data (including water content).
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JYL-1433 is a selective transient receptor potential vanilloid-1 (TRPV1) antagonist. TRPV1 is a capsaicin receptor that behaves as a non-selective cation channel that is mainly found in the sensory neurons, and specifically detects painful stimuli, low pH and heat. The compound has been shown to inhibit calcium flux and capsaicin toxicity in epitheliall cell studies.


References

1. Reilly, C.A., et al. 2005. J. Biochem. Mol. Toxicol. 19: 266-275. PMID: 16173059
2. Schumacher, M.A. and Eilers, H. 2010. Front. Biosci. 15: 872-882. PMID: 20515731

Physical State :
Solid
Solubility :
Soluble in methanol, 100% ethanol, DMSO or other organic solvents; insoluble in water.
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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Certificate of Analysis

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JYL-1433  Product Citations

See how others have used JYL-1433. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 16173059  Reilly, CA. et al. 2005. J. Biochem. Mol. Toxicol. 19: 266-275.

Citations 1 to 1 of 1 total
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