ITFG2 Antibody (F-11): sc-271420
- ITFG2 Antibody (F-11) is a mouse monoclonal IgG2a κ ITFG2 antibody, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 1-300 mapping at the N-terminus of ITFG2 of human origin
- ITFG2 Antibody (F-11) is recommended for detection of ITFG2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-ITFG2 Antibody (F-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for ITFG2 Antibody (F-11) for WB and IHC(P) applications. These reagents are now offered in bundles with ITFG2 Antibody (F-11) (see ordering information below).
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ITFG2 Antibody (F-11) is a mouse monoclonal IgG2a kappa light chain antibody that detects ITFG2 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). ITFG2 (F-11) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ITFG2, also known as Integrin-alpha FG-GAP repeat-containing protein 2, is a 447 amino acid protein characterized by the presence of two FG-GAP repeats, a motif significant in integrin function. Integrins, which are heterodimers formed from noncovalently associated transmembrane α and β subunits, play a crucial role in mediating cell adhesion and signaling. ITFG2′s interaction with other integrin subunits is essential for forming functional receptors that bind to extracellular matrix components such as fibronectin, collagen, and vitronectin, as well as soluble ligands like fibrinogen. This binding is vital for various cellular processes, including cell growth, differentiation, migration, and apoptosis. Integrin clustering and activation in response to ligand binding initiates downstream signaling pathways that influence cellular behavior. Using anti-ITFG2 antibody (F-11) in research can provide insights into integrin roles in cellular dynamics and their implications in health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ITFG2 Antibody (F-11) References:
- Integrins: versatility, modulation, and signaling in cell adhesion. | Hynes, RO. 1992. Cell. 69: 11-25. PMID: 1555235
- Large-scale mapping of human protein-protein interactions by mass spectrometry. | Ewing, RM., et al. 2007. Mol Syst Biol. 3: 89. PMID: 17353931
- Integrins and signal transduction pathways: the road taken. | Clark, EA. and Brugge, JS. 1995. Science. 268: 233-9. PMID: 7716514
- Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function. | Miyamoto, S., et al. 1995. Science. 267: 883-5. PMID: 7846531
- Epithelial integrins. | Sheppard, D. 1996. Bioessays. 18: 655-60. PMID: 8760339
- Cooperation between soluble factors and integrin-mediated cell anchorage in the control of cell growth and differentiation. | Juliano, R. 1996. Bioessays. 18: 911-7. PMID: 8939069
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ITFG2 Antibody (F-11) | sc-271420 | 200 µg/ml | $316.00 | |||
ITFG2 Antibody (F-11): m-IgG Fc BP-HRP Bundle | sc-525806 | 200 µg Ab; 10 µg BP | $354.00 | |||
ITFG2 Antibody (F-11): m-IgG2a BP-HRP Bundle | sc-546421 | 200 µg Ab; 10 µg BP | $354.00 | |||
ITFG2 Antibody (F-11) AC | sc-271420 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ITFG2 Antibody (F-11) HRP | sc-271420 HRP | 200 µg/ml | $316.00 | |||
ITFG2 Antibody (F-11) FITC | sc-271420 FITC | 200 µg/ml | $330.00 | |||
ITFG2 Antibody (F-11) PE | sc-271420 PE | 200 µg/ml | $343.00 | |||
ITFG2 Antibody (F-11) Alexa Fluor® 488 | sc-271420 AF488 | 200 µg/ml | $357.00 | |||
ITFG2 Antibody (F-11) Alexa Fluor® 546 | sc-271420 AF546 | 200 µg/ml | $357.00 | |||
ITFG2 Antibody (F-11) Alexa Fluor® 594 | sc-271420 AF594 | 200 µg/ml | $357.00 | |||
ITFG2 Antibody (F-11) Alexa Fluor® 647 | sc-271420 AF647 | 200 µg/ml | $357.00 | |||
ITFG2 Antibody (F-11) Alexa Fluor® 680 | sc-271420 AF680 | 200 µg/ml | $357.00 | |||
ITFG2 Antibody (F-11) Alexa Fluor® 790 | sc-271420 AF790 | 200 µg/ml | $357.00 |