ITF-2/TCF4 Antibody (C-1): sc-393255
- ITF-2/TCF4 Antibody (C-1) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 254-285 within an internal region of ITF-2 of human origin
- recommended for detection of ITF-2 isoforms SEF2-1A and SEF2-1D of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-393255 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ITF-2/TCF4 Antibody (C-1) for WB applications. These reagents are now offered in bundles with ITF-2/TCF4 Antibody (C-1) (see ordering information below).
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SEE ALSO...
ITF-2 Antibody (C-1) is a mouse monoclonal IgG1 antibody that detects immunoglobulin transcription factor 2 (ITF-2) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ITF-2 plays a crucial role in the regulation of gene expression, particularly in muscle development, by binding to specific DNA motifs such as the immunoglobulin enhancer Mu-E5/KE5-motif and the Ephrussi-box (E-box) element found in SSTR2-INR. Anti-ITF-2 antibody (C-1) binding activity is essential for the activation of muscle-specific genes, which are vital for proper muscle function and development. ITF-2 is predominantly expressed in tissues such as the adult heart, brain, placenta, and skeletal muscle, as well as in the embryonic brain, highlighting its importance in both developmental and adult physiology. Additionally, ITF-2 can form homo- or hetero-oligomers with other myogenic factors like myogenin and MyoD, and alternatively spliced isoforms can either activate or repress transcription, adding another layer of complexity to regulatory functions. The versatility and significance of ITF-2 in muscle gene regulation make ITF-2 monoclonal antibody (C-1) an invaluable tool for researchers studying muscle biology and related disorders.
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ITF-2/TCF4 Antibody (C-1) | sc-393255 | 200 µg/ml | $322.00 | |||
ITF-2 Antibody (C-1): m-IgG Fc BP-HRP Bundle | sc-538175 | 200 µg Ab; 10 µg BP | $361.00 | |||
ITF-2 Antibody (C-1): m-IgGκ BP-HRP Bundle | sc-535737 | 200 µg Ab; 40 µg BP | $361.00 | |||
ITF-2 Antibody (C-1): m-IgG1 BP-HRP Bundle | sc-545561 | 200 µg Ab; 20 µg BP | $361.00 | |||
ITF-2 (C-1) Neutralizing Peptide | sc-393255 P | 100 µg/0.5 ml | $69.00 | |||
ITF-2 Antibody (C-1) X | sc-393255 X | 200 µg/0.1 ml | $322.00 |