Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
IRF-2 (interferon regulatory factor-2) has been identified as a novel DNA-binding factor that functions as a regulator of both type I interferon (interferon-α and β) and interferon-inducible genes. IRF-2 may act in a mutually antagonistic manner in regulating cell growth. IRF-2BP1 (interferon regulatory factor 2 binding protein 1) is a 584 amino acid nuclear protein belonging to the IRF-2BP family. IRF-2BP1 acts as a corepressor of IRF-2 that can inhibit both enhancer-activation and basal transcription in a manner that is not dependent upon histone deacetylation. IRF-2BP1 enhances the polyubiquitination of JDP2 (Jun-dimerization protein 2), a member of the c-Jun family of transcription factors. IRF-2BP1 contains a C-terminal RING-type zinc finger domain, which is necessary for interaction with BAP1 (BRCA1 associated protein 1). IRF-2BP1 is encoded by a gene located on human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
How much sample do you recommend loading on the gel for Western blot detection using IRF-2BP1 (D-5): sc-515314?
Asked by: jerojero
We recommend loading 40–60 µg whole cell lysate, 10–20 µg nuclear extract, 5-10 µg transfected lysate, or 10–20 ng purified protein per lane. A link to our complete Western blotting protocol is provided here for your reference:
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