Ipratropium bromide monohydrate (CAS 66985-17-9)
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Ipratropium bromide monohydrate is a chemical compound that functions as an anticholinergic agent, targeting muscarinic receptors. It acts by competitively inhibiting the action of acetylcholine at these receptors, leading to a reduction in the contractility of smooth muscle in the respiratory tract. This inhibition results in bronchodilation, which may be useful for studying the physiological effects of altered smooth muscle tone in experimental models. At the molecular level, ipratropium bromide monohydrate binds to the muscarinic receptors, preventing the activation of downstream signaling pathways that would normally lead to smooth muscle constriction. This mechanism of action allows for the investigation of the specific molecular pathways involved in bronchoconstriction and the potential development of novel compounds that target these pathways.
Ipratropium bromide monohydrate (CAS 66985-17-9) References
- Physicochemical and in vitro deposition properties of salbutamol sulphate/ipratropium bromide and salbutamol sulphate/excipient spray dried mixtures for use in dry powder inhalers. | Corrigan, DO., et al. 2006. Int J Pharm. 322: 22-30. PMID: 16815654
- Electrostatic characterisation of inhaled powders: effect of contact surface and relative humidity. | Elajnaf, A., et al. 2006. Eur J Pharm Sci. 29: 375-84. PMID: 16952450
- The effect of relative humidity on electrostatic charge decay of drugs and excipient used in dry powder inhaler formulation. | Elajnaf, A., et al. 2007. Drug Dev Ind Pharm. 33: 967-74. PMID: 17891583
- Dry powder aerosols generated by standardized entrainment tubes from drug blends with lactose monohydrate: 2. Ipratropium bromide monohydrate and fluticasone propionate. | Xu, Z., et al. 2010. J Pharm Sci. 99: 3415-29. PMID: 20222025
- Clinical efficacy and safety of the combination of ipratropium bromide and fenoterol inhaled via the Respimat Soft Mist inhaler for relief of airflow obstruction. | Vincken, W. 2008. Expert Rev Respir Med. 2: 11-26. PMID: 20477218
- A comparative study of various combinations of ipratropium bromide and metaproterenol in allergic asthmatic patients. | Bruderman, I., et al. 1983. Chest. 83: 208-10. PMID: 6217951
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ipratropium bromide monohydrate, 250 mg | sc-252911 | 250 mg | $87.00 |