Integrin β7/ITGB7 Antibody (D-5): sc-515397

Integrin β7 Antibody (D-5) is a mouse monoclonal IgG2a antibody that detects Integrin β7 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Integrin β7 Antibody (D-5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Integrin β7 is a crucial component of the integrin family, which consists of heterodimers formed by noncovalently associated transmembrane α and β subunits. The specific structure of Integrin β7 allows interaction with various ligands, including components of the extracellular matrix such as fibronectin and collagen, as well as soluble ligands like fibrinogen. This interaction mediates cell adhesion and signaling, essential for processes such as cell migration, differentiation, and survival. Integrin β7′s ability to bind to counterreceptors on adjacent cells, such as intracellular adhesion molecules (ICAMs), facilitates cell aggregation and communication, highlighting Integrin β7′s role in maintaining tissue integrity and immune responses. Anti-Integrin β7 antibody (D-5) enables researchers to explore this integrin′s function in various biological processes and disease states.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Integrin β7/ITGB7 Antibody (D-5) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-Integrin β7/ITGB7 Antibody (D-5) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Integrin β7/ITGB7 Antibody (D-5) Specifications

Alternate Product Name: Integrin β7

Product Clone Name: D-5

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a lambda light chain

Amino Acids: 775-798

Epitope Target: Integrin β7

Epitope Species: human

Product Reactivity/Detection: Integrin β7

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG_2a lambda light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for Integrin β7/ITGB7 Antibody (D-5): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin

The preferred Integrin β7/ITGB7 antibody is Integrin β7/ITGB7 Antibody (FIB504): sc-23919.