Integrin β4/ITGB4/CD104 Antibody (G-7): sc-13127
- Integrin β4/ITGB4/CD104 Antibody (G-7) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 28-128 of Integrin β4 of human origin
- recommended for detection of Integrin β4 of human origin by WB, IP, IF, FCM and ELISA
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for Integrin β4/ITGB4/CD104 Antibody (G-7) for WB applications. This reagent is now offered in a bundle with Integrin β4/ITGB4/CD104 Antibody (G-7) (see ordering information below).
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Integrin β4 Antibody (G-7) is a mouse monoclonal IgG1 antibody that detects Integrin β4 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Integrin β4, also known as CD104, is a crucial component of the integrin family, consisting of 1,822 amino acids and functioning as a single-pass type I membrane protein. Anti-Integrin β4 antibody (G-7) recognizes a protein that plays a vital role in cell adhesion and signaling, primarily by serving as a receptor for Laminin, which is essential for maintaining the structural integrity of epithelial tissues. The interaction between Integrin β4 and Laminin is particularly important for the stability of the basement membrane, influencing processes such as cell migration, differentiation, and tissue repair. Additionally, Integrin β4 exists in five alternatively spliced isoforms, which adds complexity to its functional roles in various cellular contexts. The gene encoding Integrin β4 is located on human chromosome 17q25.1, and expression is predominantly found in epithelial cells, highlighting significance in maintaining epithelial architecture and function. Integrin β4 monoclonal antibody (G-7) is an invaluable tool for researchers studying cell adhesion mechanisms and the role of integrins in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Integrin β4/ITGB4/CD104 Antibody (G-7) | sc-13127 | 200 µg/ml | $316.00 | |||
Integrin β4/ITGB4/CD104 Antibody (G-7): m-IgG Fc BP-HRP Bundle | sc-538894 | 200 µg Ab; 10 µg BP | $354.00 |