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Integrin β2 Antibody (MEM-48) is a mouse monoclonal IgG1 antibody that detects Integrin β2 in human samples through western blotting (WB) under non-reducing conditions, immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Integrin β2 is a crucial component of the integrin family, which consists of heterodimers formed by noncovalently associated transmembrane α and β subunits. Specifically, anti-Integrin β2 antibody (MEM-48) recognizes receptors that pair with various α subunits to play a vital role in cell adhesion and signaling. Integrin β2 is predominantly located on the cell surface, where Integrin β2 interacts with ligands in the extracellular matrix, such as Fibronectin and Collagen, as well as with counterreceptors on adjacent cells, facilitating cellular communication and aggregation. This localization is essential for maintaining tissue integrity and mediating responses to the extracellular environment. Furthermore, Integrin β2 is involved in critical biological processes, including cell migration, differentiation, and apoptosis, making Integrin β2 a key player in immune responses and inflammation. Anti-Integrin β2 antibody (MEM-48) serves as an invaluable tool for researchers studying these complex cellular mechanisms and the role of integrins in various physiological and pathological conditions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Integrin β2/ITGB2/CD18 Antibody (MEM-48) | sc-51652 | 100 µg/ml | $322.00 | |||
Integrin β2/ITGB2/CD18 Antibody (MEM-48) L | sc-51652 L | 100 µg/0.1 ml | $322.00 |