Integrin β2/ITGB2/CD18 Antibody (C71/16): sc-65874

Integrin β2 Antibody (C71/16) is a rat monoclonal IgG2a antibody that detects Integrin β2 in mouse samples through applications such as western blotting (WB) and immunoprecipitation (IP). Integrin β2 (C71/16) antibody was raised against cell membrane proteins purified from BW5147 cells of mouse origin. Integrin β2 (C71/16) monoclonal antibody is a crucial component of the integrin family, which consists of heterodimeric receptors that mediate cell adhesion and signaling. Anti-Integrin β2 antibody (C71/16) is primarily located on the cell surface, where this protein plays a vital role in connecting the extracellular matrix to the cytoskeleton, facilitating communication between internal and external environments of the cell. Proper localization of Integrin β2 (C71/16) monoclonal antibody is essential for various cellular processes, including migration, proliferation, and survival, as this protein allows cells to respond to their surroundings effectively. Anti-Integrin β2 antibody (C71/16) interacts with several key proteins, such as ICAMs (intercellular adhesion molecules), which are important for leukocyte adhesion and immune response. Integrin β2 forms complexes with these proteins, underscoring significance in maintaining cellular interactions and orchestrating immune functions. Integrin β2 undergoes post-translational modifications such as glycosylation, which is crucial for proper folding, stability, and functional interactions with extracellular ligands and intracellular signaling partners, thereby ensuring effective immune cell adhesion and migration. Anti-Integrin β2 antibody (C71/16) enables researchers to gain insights into the dynamics of cell adhesion and signaling pathways, contributing to a better understanding of various physiological and pathological processes.

The preferred Integrin β2/ITGB2/CD18 antibody is Integrin β2/ITGB2/CD18 Antibody (CTB104): sc-8420.