Integrin β1/ITGB1 Antibody (P5D2): sc-13590

Integrin β1 Antibody (P5D2) is a mouse monoclonal IgG1 kappa light chain antibody that detects Integrin β1 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Anti-Integrin β1 antibody (P5D2) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Integrin β1 plays a crucial role in cell adhesion and signaling, functioning as a key component of integrin receptors that mediate interactions between cells and the extracellular matrix. Integrin β1 is primarily located on the cell surface, where Integrin β1 forms heterodimers with various alpha subunits, allowing binding to ligands such as fibronectin, collagen, and vitronectin. Proper localization of Integrin β1 is essential for maintaining tissue architecture and facilitating cellular communication, as Integrin β1 enables cells to respond to their microenvironment and influences processes such as cell migration, proliferation, and survival. Furthermore, interaction of Integrin β1 with ligands is vital for the activation of downstream signaling pathways that regulate critical biological functions, making Integrin β1 an important target for research in cancer, wound healing, and immune responses.

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Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Integrin β1/ITGB1 Antibody (P5D2) has 84 citations in a variety of scientific publications.

Primary antibodies like Anti-Integrin β1/ITGB1 Antibody (P5D2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Integrin β1/ITGB1 Antibody (P5D2) Specifications

Alternate Product Name: CD29

Product Clone Name: P5D2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids:

Epitope Target: Integrin β1

Epitope Species: human

Product Reactivity/Detection: Integrin β1

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, FCM

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 84 citations in various scientific publications

Available Conjugates/Forms for Integrin β1/ITGB1 Antibody (P5D2): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, L: Azide-Free, PE: Phycoerythrin

The preferred Integrin β1/ITGB1 antibody is Integrin β1/ITGB1 Antibody (K-20): sc-18887.