Integrin β1/ITGB1 Antibody (P4G11): sc-18845

Integrin β1 Antibody (P4G11) is a mouse monoclonal IgG1 antibody that detects Integrin β1 in human samples through flow cytometry (FCM). Integrin β1 is a crucial component of the integrin family, which consists of heterodimeric receptors formed by the noncovalent association of α and β subunits. Integrin β1 plays a vital role in mediating cell adhesion to the extracellular matrix and is essential for various cellular processes, including migration, proliferation, and survival. Integrin β1 is predominantly located on the cell surface, where Integrin β1 interacts with extracellular matrix components such as fibronectin and collagen, facilitating the attachment of cells to their surrounding environment. This interaction is not only important for maintaining tissue architecture but also for transmitting signals that influence cellular behavior, making Integrin β1 a key player in processes such as wound healing and immune responses. Additionally, Integrin β1 undergoes post-translational modifications, including glycosylation, which can affect function and interactions with other proteins. The ability of Integrin β1 to form complexes with various α subunits allows for the generation of multiple integrin receptors, each with distinct ligand-binding properties, thereby expanding functional repertoire in cellular signaling and adhesion. Anti-Integrin β1 antibody (P4G11) is an invaluable tool for researchers studying the dynamics of cell adhesion and signaling pathways in human cells.

The preferred Integrin β1/ITGB1 antibody is Integrin β1/ITGB1 Antibody (K-20): sc-18887.