Integrin β1/ITGB1 Antibody (E-11): sc-374430

Integrin β1 Antibody (E-11) is a mouse monoclonal IgG2a kappa light chain antibody that detects Integrin β1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Integrin β1 antibody (E-11) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Integrin β1 is a crucial component of integrin receptors, which are heterodimers formed by noncovalently associated transmembrane α and β subunits. The presence of 16 α and 8 β subunits allows for the formation of over 20 distinct integrin receptors, each playing a vital role in cell adhesion and communication with the extracellular matrix. These receptors are essential for binding ligands such as fibronectin, collagen, and vitronectin, which are integral to maintaining tissue structure and facilitating cellular interactions. Integrin β1 is involved in signaling pathways that regulate various biological processes, including cell growth, differentiation, migration, and apoptosis. The ability of integrins to cluster and activate in response to ligand binding is critical for initiating these signaling cascades, making Integrin β1 a key player in cellular responses to the extracellular environment.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Integrin β1/ITGB1 Antibody (E-11) has 9 citations in a variety of scientific publications.

Primary antibodies like Anti-Integrin β1/ITGB1 Antibody (E-11) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Integrin β1/ITGB1 Antibody (E-11) Specifications

Alternate Product Name: CD29

Product Clone Name: E-11

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 375-480

Epitope Target: Integrin β1

Epitope Species: human

Product Reactivity/Detection: Integrin β1

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 9 citations in various scientific publications

Available Conjugates/Forms for Integrin β1/ITGB1 Antibody (E-11): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred Integrin β1/ITGB1 antibody is Integrin β1/ITGB1 Antibody (K-20): sc-18887.