Influenza B NP Antibody (IB633): sc-66104

Influenza B NP Antibody (IB633) is a mouse monoclonal IgG1 antibody that detects Influenza B NP of Influenza B Virus by western blotting (WB). Influenza B NP, or nucleoprotein, plays a crucial role in the viral life cycle, as it is essential for the encapsidation of viral RNA and the formation of viral ribonucleoprotein complexes. Influenza B NP not only protects viral RNA from degradation but also facilitates RNA transport within the host cell, ensuring efficient replication and transcription of the viral genome. Anti-Influenza B NP antibody (IB633) recognizes a protein that interacts with other viral proteins, such as hemagglutinin and neuraminidase, which is vital for the assembly and release of new virions, making Influenza B NP a key target for therapeutic interventions and vaccine development. Influenza B NP monoclonal antibody (IB633) helps researchers gain insights into the dynamics of Influenza B virus infections and the mechanisms by which the virus evades host immune responses, ultimately contributing to the development of more effective antiviral strategies.

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Influenza B NP Antibody (IB633) References:

1. Nuclear import of influenza B virus nucleoprotein: involvement of an N-terminal nuclear localization signal and a cleavage-protection motif.  |  Wanitchang, A., et al. 2013. Virology. 443: 59-68. PMID: 23689061
2. Nucleoprotein of influenza B virus binds to its type A counterpart and disrupts influenza A viral polymerase complex formation.  |  Jaru-ampornpan, P., et al. 2014. Biochem Biophys Res Commun. 443: 296-300. PMID: 24309113
3. The N terminus of the influenza B virus nucleoprotein is essential for virus viability, nuclear localization, and optimal transcription and replication of the viral genome.  |  Sherry, L., et al. 2014. J Virol. 88: 12326-38. PMID: 25122787
4. High Inter-Individual Diversity of Point Mutations, Insertions, and Deletions in Human Influenza Virus Nucleoprotein-Specific Memory B Cells.  |  Reiche, S., et al. 2015. PLoS One. 10: e0128684. PMID: 26086076
5. The Functional Study of the N-Terminal Region of Influenza B Virus Nucleoprotein.  |  Liu, M., et al. 2015. PLoS One. 10: e0137802. PMID: 26368391
6. Structural analysis of the complex between influenza B nucleoprotein and human importin-α.  |  Labaronne, A., et al. 2017. Sci Rep. 7: 17164. PMID: 29215074
7. Broad Spectrum Inhibitor of Influenza A and B Viruses Targeting the Viral Nucleoprotein.  |  White, KM., et al. 2018. ACS Infect Dis. 4: 146-157. PMID: 29268608
8. Non-Uniform and Non-Random Binding of Nucleoprotein to Influenza A and B Viral RNA.  |  Le Sage, V., et al. 2018. Viruses. 10: PMID: 30257455
9. Single mucosal vaccination targeting nucleoprotein provides broad protection against two lineages of influenza B virus.  |  Kim, MH., et al. 2019. Antiviral Res. 163: 19-28. PMID: 30639307
10. Pre-clinically evaluated visual lateral flow platform using influenza A and B nucleoprotein as a model and its potential applications.  |  Wiriyachaiporn, N., et al. 2021. RSC Adv. 11: 18597-18604. PMID: 35480952

The preferred Influenza B NP antibody is Influenza B NP Antibody (B017): sc-57885.