IL-32 Antibody (AT2F9): sc-517408

IL-32 Antibody (AT2F9) is a mouse monoclonal IgG1 kappa light chain antibody that detects IL-32 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-IL-32 antibody (AT2F9) is available as a non-conjugated format, providing researchers with a reliable tool for studying this important cytokine. IL-32 plays a crucial role in the immune response, particularly in the regulation of inflammation and the modulation of various immune cell functions. IL-32 is primarily expressed in activated T cells and has been implicated in several inflammatory diseases, including rheumatoid arthritis and psoriasis. Understanding IL-32 function is vital, as IL-32 not only influences the production of other pro-inflammatory cytokines but also interacts with specific proteins such as TNF-alpha and IL-6, further amplifying inflammatory responses. The ability of IL-32 to modulate these pathways highlights IL-32′s potential as a therapeutic target in treating chronic inflammatory conditions.

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IL-32 Antibody (AT2F9) References:

1. Interleukin-32: a cytokine and inducer of TNFalpha.  |  Kim, SH., et al. 2005. Immunity. 22: 131-42. PMID: 15664165
2. IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism.  |  Netea, MG., et al. 2005. Proc Natl Acad Sci U S A. 102: 16309-14. PMID: 16260731
3. Proteinase 3 is an IL-32 binding protein.  |  Novick, D., et al. 2006. Proc Natl Acad Sci U S A. 103: 3316-21. PMID: 16488976
4. IL-32, a proinflammatory cytokine in rheumatoid arthritis.  |  Joosten, LA., et al. 2006. Proc Natl Acad Sci U S A. 103: 3298-303. PMID: 16492735
5. Identification of a novel gene expressed in activated natural killer cells and T cells.  |  Dahl, CA., et al. 1992. J Immunol. 148: 597-603. PMID: 1729377

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-IL-32 Antibody (AT2F9) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-IL-32 Antibody (AT2F9) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

IL-32 Antibody (AT2F9) Specifications

Alternate Product Name: IL-32

Product Clone Name: AT2F9

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 1-131

Epitope Target: IL-32

Epitope Species: human

Product Reactivity/Detection: IL-32

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 100 µg IgG₁ kappa light chain in 1.0 ml of PBS with 0.02% sodium azide and 10% glycerol

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for IL-32 Antibody (AT2F9): N/A