Date published: 2025-10-19

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IL-1α Antibody (5G3): sc-130325

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Datasheets
  • IL-1α Antibody (5G3) is a mouse monoclonal IgG1, cited in 3 publications, provided at 200 µg/ml
  • raised against recombinant IL-1α of human origin
  • recommended for detection of IL-1α of human origin by WB, IP, IF and IHC(P)
  • See IL-1α (ALF-161): sc-12741 for IL-1α antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for IL-1α Antibody (5G3). This work is in progress.

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IL-1α Antibody (5G3) is a mouse monoclonal IgG1 antibody that detects interleukin-1α (IL-1α) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. IL-1α monoclonal antibody (5G3) recognizes a pivotal cytokine that plays a crucial role in mediating inflammatory responses and regulating immune functions. IL-1α is primarily produced by activated macrophages and is involved in various physiological processes, including the activation of T and B lymphocytes, as well as natural killer (NK) cells. IL-1α is secreted and can be found in the extracellular space, where binding to the interleukin-1 receptor triggers a cascade of signaling events that lead to the production of other pro-inflammatory cytokines. Anti-IL-1α antibody (5G3) helps researchers study immune responses, as IL-1α not only promotes inflammation but also influences the differentiation of immune cells, thereby shaping the overall immune landscape. Dysregulation of IL-1α has been implicated in several chronic inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease, highlighting IL-1α′s significance as a therapeutic target. IL-1α (5G3) antibody serves as an essential tool for researchers studying the intricate roles of this cytokine in health and disease.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

IL-1α Antibody (5G3)

sc-130325
200 µg/ml
$316.00

Can sc-130325: IL-1α (5G3) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: AbPolly
Thank you for your question. Yes, sc-130325: IL-1α (5G3) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-03-24
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Rated 4 out of 5 by from Worked great for WB with human recombinant ILWorked great for WB with human recombinant IL-1 .
Date published: 2014-05-31
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IL-1α Antibody (5G3) is rated 4.0 out of 5 by 1.
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