IL-1α Antibody (5G3) is a mouse monoclonal IgG1 antibody that detects interleukin-1α (IL-1α) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. IL-1α monoclonal antibody (5G3) recognizes a pivotal cytokine that plays a crucial role in mediating inflammatory responses and regulating immune functions. IL-1α is primarily produced by activated macrophages and is involved in various physiological processes, including the activation of T and B lymphocytes, as well as natural killer (NK) cells. IL-1α is secreted and can be found in the extracellular space, where binding to the interleukin-1 receptor triggers a cascade of signaling events that lead to the production of other pro-inflammatory cytokines. Anti-IL-1α antibody (5G3) helps researchers study immune responses, as IL-1α not only promotes inflammation but also influences the differentiation of immune cells, thereby shaping the overall immune landscape. Dysregulation of IL-1α has been implicated in several chronic inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease, highlighting IL-1α′s significance as a therapeutic target. IL-1α (5G3) antibody serves as an essential tool for researchers studying the intricate roles of this cytokine in health and disease.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IL-1α Antibody (5G3) | sc-130325 | 200 µg/ml | $316.00 |