IL-12Rβ1 Antibody (DU-1): sc-13511
- IL-12Rβ1 Antibody (DU-1) is a rat monoclonal IgG2a, cited in 1 publications, provided at 200 µg/ml
- raised against IL-12 receptor β1 of human origin
- recommended for detection of IL-12Rβ1 of human origin by WB and IP
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for IL-12Rβ1 Antibody (DU-1). This work is in progress.
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IL-12Rβ1 Antibody (DU-1) is a rat monoclonal IgG2a antibody that detects IL-12Rβ1 in human samples through western blotting (WB) and immunoprecipitation (IP) applications. IL-12Rβ1 is a critical component of the interleukin-12 receptor complex, which plays a vital role in the immune response by mediating the effects of the cytokine IL-12 on T cells and natural killer (NK) cells. This receptor is primarily located on the surface of immune cells, including T cells and NK cells, where IL-12Rβ1 facilitates the binding of IL-12, leading to the activation and proliferation of these cells. The proper functioning of IL-12Rβ1 is essential for the differentiation of T-helper 1 (Th1) cells, which are crucial for mounting effective immune responses against intracellular pathogens. Dysregulation of IL-12Rβ1 expression can contribute to various autoimmune diseases, highlighting IL-12Rβ1′s importance in maintaining immune homeostasis. IL-12Rβ1 monoclonal antibody (DU-1) enables researchers to gain insights into the mechanisms of immune regulation and the potential therapeutic targets for conditions associated with Th1-mediated pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IL-12Rβ1 Antibody (DU-1) | sc-13511 | 200 µg/ml | $316.00 | |||
IL-12Rβ1 Antibody (DU-1) FITC | sc-13511 FITC | 200 µg/ml | $330.00 | |||
IL-12Rβ1 Antibody (DU-1) PE | sc-13511 PE | 200 µg/ml | $343.00 |