IgG4 Antibody (5C7): sc-52007
- IgG4 Antibody (5C7) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against IgG4 from human serum
- recommended for detection of Fc-region of IgG4 of human origin by ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for IgG4 Antibody (5C7). This work is in progress.
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SEE ALSO...
IgG4 Antibody (5C7) is a mouse monoclonal IgG1 antibody that detects the IgG4 protein of human origin by enzyme-linked immunosorbent assay (ELISA). IgG4 is a unique subclass of immunoglobulin G that plays a crucial role in the immune response, particularly in modulating allergic reactions and autoimmune diseases. Unlike other IgG subclasses, IgG4 is known for its ability to undergo a process called "Fab-arm exchange," which allows IgG4 to form bispecific antibodies that can bind to two different antigens simultaneously. This characteristic is significant as IgG4 can help in regulating immune responses and reducing inflammation, making IgG4 an important player in maintaining immune tolerance. Furthermore, research has indicated that low concentrations of IgG4 are often found in patients with recurrent respiratory tract infections, suggesting IgG4′s potential role in immune system dysfunction. Anti-IgG4 antibody (5C7) is an essential tool for researchers studying the complexities of the immune system and the implications of IgG4 in various diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IgG4 Antibody (5C7) | sc-52007 | 100 µg/ml | $316.00 |