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IgA1 Antibody (2B5) is a mouse monoclonal IgM antibody that detects the IgA1 protein of human origin by enzyme-linked immunosorbent assay (ELISA). Anti-IgA1 antibody (2B5) is available as the non-conjugated format. IgA1, or immunoglobulin A1, plays a crucial role as a first line of defense against microbial pathogens, particularly in mucosal areas such as the respiratory and gastrointestinal tracts. IgA1 is primarily located in secretions like saliva, tears, and mucosal surfaces, where IgA1 helps neutralize pathogens and prevent their entry into the body. The unique structure of IgA1, which includes a secretory component that protects IgA1 from proteolytic degradation, is vital for function in these environments. Additionally, IgA1 undergoes post-translational modifications, such as glycosylation, which enhance stability and functionality, allowing IgA1 to effectively bind to antigens and facilitate immune responses. With an ability to provide critical immune protection, IgA1 is essential for maintaining mucosal immunity and overall health.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IgA1 Antibody (2B5) | sc-51990 | 100 µg/ml | $316.00 |