IFT81 Antibody (A-3): sc-374272
- IFT81 Antibody (A-3) is a mouse monoclonal IgG2b κ IFT81 antibody provided at 200 µg/ml
- raised against amino acids 377-676 mapping at the C-terminus of IFT81 of human origin
- IFT81 Antibody (A-3) is recommended for detection of IFT81 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-IFT81 Antibody (A-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for IFT81 Antibody (A-3). This work is in progress.
QUICK LINKS
IFT81 Antibody (A-3) is a mouse monoclonal IgG2b kappa light chain antibody that detects IFT81 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). IFT81 (A-3) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. IFT81, also known as intraflagellar transport 81 or CDV1 (carnitine deficiency-associated protein expressed in ventricle 1), consists of 676 amino acids and is predominantly expressed in the testis, with moderate levels found in the heart, liver, ovary, pancreas, kidney, and skeletal muscle. IFT81 is crucial for intraflagellar transport, which is essential for the assembly and maintenance of cilia and flagella, structures that play vital roles in cellular signaling and motility. Disruptions in IFT81 function can lead to defects in cilia formation, which are associated with a range of developmental disorders and diseases, including those affecting the respiratory and reproductive systems. The gene encoding IFT81 is located on human chromosome 12, a region that harbors over 1,100 genes and is linked to various genetic disorders, such as hypochondrogenesis and Noonan syndrome.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
IFT81 Antibody (A-3) References:
- Genomic organization and mapping of mouse CDV (carnitine deficiency-associated gene expressed in ventricle)-1 and its related CDV-1R gene. | Higashi, M., et al. 2000. Mamm Genome. 11: 1053-7. PMID: 11130971
- Identification of human CDV-1R and mouse Cdv-1R, two novel proteins with putative signal peptides, especially highly expressed in testis and increased with the male sex maturation. | Peng, J., et al. 2002. Mol Biol Rep. 29: 353-62. PMID: 12549821
- Expression of Cdv-iR gene in mouse epididymis as revealed by in situ hybridization. | Zhang, KX., et al. 2005. Arch Androl. 51: 7-13. PMID: 15764413
- Characterization of the intraflagellar transport complex B core: direct interaction of the IFT81 and IFT74/72 subunits. | Lucker, BF., et al. 2005. J Biol Chem. 280: 27688-96. PMID: 15955805
- A novel gene suppressed in the ventricle of carnitine-deficient juvenile visceral steatosis mice. | Masuda, M., et al. 1997. FEBS Lett. 408: 221-4. PMID: 9187371
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IFT81 Antibody (A-3) | sc-374272 | 200 µg/ml | $316.00 | |||
IFT81 Antibody (A-3) AC | sc-374272 AC | 500 µg/ml, 25% agarose | $416.00 | |||
IFT81 Antibody (A-3) HRP | sc-374272 HRP | 200 µg/ml | $316.00 | |||
IFT81 Antibody (A-3) FITC | sc-374272 FITC | 200 µg/ml | $330.00 | |||
IFT81 Antibody (A-3) PE | sc-374272 PE | 200 µg/ml | $343.00 | |||
IFT81 Antibody (A-3) Alexa Fluor® 488 | sc-374272 AF488 | 200 µg/ml | $357.00 | |||
IFT81 Antibody (A-3) Alexa Fluor® 546 | sc-374272 AF546 | 200 µg/ml | $357.00 | |||
IFT81 Antibody (A-3) Alexa Fluor® 594 | sc-374272 AF594 | 200 µg/ml | $357.00 | |||
IFT81 Antibody (A-3) Alexa Fluor® 647 | sc-374272 AF647 | 200 µg/ml | $357.00 | |||
IFT81 Antibody (A-3) Alexa Fluor® 680 | sc-374272 AF680 | 200 µg/ml | $357.00 | |||
IFT81 Antibody (A-3) Alexa Fluor® 790 | sc-374272 AF790 | 200 µg/ml | $357.00 |