Anti-IFN-γRβ Antibody (A-11) is a mouse monoclonal IgG1 (kappa light chain) IFN-γRβ antibody provided at 200 µg/ml
raised against amino acids 28-337 of IFN-γRβ of human origin
IFN- gamma R beta Antibody (A-11) is recommended for detection of IFN-γRβ of human origin by WB, IP, IF and ELISA
Anti-IFN- gamma R beta Antibody (A-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of IFN-γRβ (A-11): sc-377291.
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
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Labware ships FedEx Ground free of charge to the contiguous US
IFN-γRβ Antibody (A-11) is a high quality monoclonal IFN- gamma R beta antibody (also designated IFN-γRβ antibody) suitable for the detection of the IFN- gamma R beta protein of human origin. IFN-γRβ Antibody (A-11) is available as both the non-conjugated anti-IFN- gamma R beta antibody form, as well as multiple conjugated forms of anti-IFN- gamma R beta antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. IFN-γ induces a variety of biological responses, such as antiviral, antiproliferative and immunomodulatory activity in sensitive cells. Activation of the IFN-γ receptor (IFN-γR) leads to autophosphorylation of the Janus kinases JAK1 and JAK2, and the nuclear translocation of the transcription factors Stat1α p91 and Stat1β p84. The IFN-γR is composed of at least two chains, designated IFN-γRα and IFN-γRβ, respectively. Although expression of IFN-γRα is sufficient for ligand binding, it alone does not confer responsiveness to IFN-γ. Concomitant expression of IFN-γRα and IFN-γRβ is required for transcriptional activation of IFN-γ-inducible genes. The IFN-γRβ chain, also called AF-1, is 332 and 337 amino acids in length in mouse and human, respectively, and may represent the signal transducing component of the IFN-γR.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
What is the recommended starting dilution for Western blot for sc-377291: IFN-γRβ (A-11) monoclonal antibody?
Asked by: jerojero
The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, is available in the recommended protocol:
Rated 5 out of
Produced positive Western blot data of IFNProduced positive Western blot data of IFN- R expression in non-transfected and human IFN- R transfected 293T whole cell lysates. -SCBT QC
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