IFN-γ/Interferon gamma Antibody (LLO6Z): sc-74108

IFN-γ Antibody (LLO6Z) is a mouse monoclonal IgG2b antibody that detects interferon gamma (IFN-γ) in human samples through applications such as immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). IFN-γ plays a crucial role in the immune response, acting as a potent antiviral and antiparasitic agent produced by activated CD4+/CD8+ lymphocytes and natural killer cells. The importance of IFN-γ lies in its ability to modulate T cell growth and differentiation while inhibiting B cell proliferation, thereby orchestrating a balanced immune response. The protein′s active form is a homodimer, with each subunit comprising six helices, and this dimeric structure is stabilized by non-covalent interactions at the interface of the helices. The precursor of IFN-γ consists of 166 amino acids, which includes a 23 amino acid secretory sequence, and IFN-γ functionality is further enhanced by variable glycosylation, leading to multiple forms under non-denaturing conditions, including dimers and tetramers. The versatility of IFN-γ in mediating immune responses makes IFN-γ a critical target for research and therapeutic applications, and IFN-γ (LLO6Z) monoclonal antibody is an essential tool for studying its role in various biological processes.

The preferred IFN-γ/Interferon gamma antibody is IFN-γ/Interferon gamma Antibody (G-23): sc-8423.