IFN-γ/Interferon gamma Antibody (500-M90): sc-65352
- IFN-γ/Interferon gamma Antibody (500-M90) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against recombinant IFN γ of human origin
- recommended for detection of IFN gamma of human origin by WB, IP and ELISA
- See IFN-γ/Interferon gamma (E-10): sc-373727 for IFN-γ/Interferon gamma antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for IFN-γ/Interferon gamma Antibody (500-M90). This work is in progress.
IFN-γ Antibody (500-M90) is a mouse monoclonal IgG1 antibody that detects interferon gamma (IFN-γ) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). IFN-γ plays a crucial role in the immune response, acting as a potent antiviral and antiparasitic agent produced by activated CD4+/CD8+ lymphocytes and natural killer cells. Production of IFN-γ is stimulated by various factors, including interleukin-2, fibroblast growth factor, and epidermal growth factor, which underscores IFN-γ′s importance in modulating T cell growth and differentiation while inhibiting B cell proliferation. IFN-γ exists primarily as a homodimer, with each subunit comprising six helices, and this dimeric structure is essential for biological activity, as IFN-γ is stabilized by non-covalent interactions at the interface of the helices. The precursor of IFN-γ consists of 166 amino acids, including a 23 amino acid secretory sequence, and IFN-γ functionality is further influenced by post-translational modifications such as glycosylation, which can lead to the formation of multiple isoforms under non-denaturing conditions, including dimers and tetramers. The versatility of IFN-γ in immune regulation makes IFN-γ a critical target for research and therapeutic applications, and anti-IFN-γ antibody (500-M90) is an invaluable tool for studying IFN-γ′s role in various biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IFN-γ/Interferon gamma Antibody (500-M90) | sc-65352 | 100 µg/ml | $316.00 |