IFN-β Antibody (A1): sc-53968
- IFN-β Antibody (A1) is a mouse monoclonal IgG1 κ IFN-β antibody, cited in 2 publications, provided at 200 µg/ml
- raised against recombinant IFN-β of human origin
- IFN-beta Antibody (A1) is recommended for detection of IFN-β of human origin by WB and IP; non cross-reactive with human IFNα or IFN-γ or mouse IFN-β
- Anti-IFN-beta Antibody (A1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for IFN-β Antibody (A1) for WB applications. These reagents are now offered in bundles with IFN-β Antibody (A1) (see ordering information below).
IFN-β Antibody (A1) is a mouse monoclonal IgG1 kappa light chain antibody that detects human IFN-β by western blotting (WB) and immunoprecipitation (IP). Anti-IFN-β antibody (A1) is raised against recombinant human IFN-β. IFN-β monoclonal antibody (A1) is available in non-conjugated and conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, offering versatility for various experimental needs. Anti-IFN-β antibody (A1) interacts with the type I interferon receptor (IFNAR), composed of IFNAR1 and IFNAR2 subunits, which recruit and activate JAK1 and TYK2 kinases, initiating downstream signaling through STAT proteins to regulate antiviral and immune responses. IFN-β plays a crucial role in immune response, particularly in regulating antiviral activity, making IFN-β essential for defense against viral infections. IFN-β is produced by fibroblasts and leukocytes in response to viral infections and other stimuli, and IFN-β signaling through IFNAR leads to activation of numerous genes involved in antiviral defense. This signaling pathway enhances immune response and has implications in treating various diseases, including certain cancers and autoimmune disorders. Type I interferon genes, including IFN-β, are clustered on human chromosome 9, and understanding IFN-β expression and regulation can provide insights into therapeutic strategies for enhancing immune responses.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IFN-β Antibody (A1) | sc-53968 | 200 µg/ml | $322.00 | |||
IFN-β Antibody (A1): m-IgG Fc BP-HRP Bundle | sc-526854 | 200 µg Ab; 10 µg BP | $361.00 | |||
IFN-β Antibody (A1): m-IgG1 BP-HRP Bundle | sc-532227 | 200 µg Ab; 20 µg BP | $361.00 | |||
IFN-β Antibody (A1) AC | sc-53968 AC | 500 µg/ml, 25% agarose | $424.00 | |||
IFN-β Antibody (A1) HRP | sc-53968 HRP | 200 µg/ml | $322.00 | |||
IFN-β Antibody (A1) FITC | sc-53968 FITC | 200 µg/ml | $336.00 | |||
IFN-β Antibody (A1) PE | sc-53968 PE | 200 µg/ml | $349.00 | |||
IFN-β Antibody (A1) Alexa Fluor® 488 | sc-53968 AF488 | 200 µg/ml | $364.00 | |||
IFN-β Antibody (A1) Alexa Fluor® 546 | sc-53968 AF546 | 200 µg/ml | $364.00 | |||
IFN-β Antibody (A1) Alexa Fluor® 594 | sc-53968 AF594 | 200 µg/ml | $364.00 | |||
IFN-β Antibody (A1) Alexa Fluor® 647 | sc-53968 AF647 | 200 µg/ml | $364.00 | |||
IFN-β Antibody (A1) Alexa Fluor® 680 | sc-53968 AF680 | 200 µg/ml | $364.00 | |||
IFN-β Antibody (A1) Alexa Fluor® 790 | sc-53968 AF790 | 200 µg/ml | $364.00 |