IAP Antibody (AP1B9) is a mouse monoclonal IgG1 antibody that detects intestinal alkaline phosphatase (IAP) in bovine samples through immunofluorescence (IF) applications. Anti-IAP antibody (AP1B9) plays a crucial role in studying the digestive system′s brush-border enzyme, which is significantly upregulated during the differentiation of small intestinal epithelial cells. IAP is essential for limiting fat absorption and is involved in the trans-cellular transport and formation of chylomicrons, which are vital for lipid metabolism. IAP operates optimally at high pH levels, where IAP removes phosphate groups from proteins and the 5′ ends of DNA and RNA, thereby influencing various biochemical pathways. IAP is particularly notable in tissues such as the liver, bile ducts, placenta, and bone, with IAP levels serving as a potential biomarker for various conditions, including bone and liver diseases. Additionally, serum IAP levels can vary among different ABO blood groups, with individuals of blood group O or B exhibiting higher prevalence, which may also affect fatty acid metabolism. IAP (AP1B9) monoclonal antibody is an invaluable tool for researchers studying the intricate roles of intestinal alkaline phosphatase in bovine models, providing insights into its function and implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IAP Antibody (AP1B9) | sc-53335 | 200 µg/ml | $322.00 |