Molecular structure of Hydroxy Ritonavir, CAS Number: 176655-56-4
Hydroxy Ritonavir (CAS 176655-56-4)
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Application:
Hydroxy Ritonavir is A metabolite of the selective HIV-1 protease inhibitor Ritonavir
CAS Number:
176655-56-4
Molecular Weight:
736.94
Molecular Formula:
C37H48N6O6S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Hydroxy Ritonavir is a metabolite of the selective HIV protease inhibitor Ritonavir.
Hydroxy Ritonavir (CAS 176655-56-4) References
- Inhibition of the CYP3A4-mediated metabolism and P-glycoprotein-mediated transport of the HIV-1 protease inhibitor saquinavir by grapefruit juice components. | Eagling, VA., et al. 1999. Br J Clin Pharmacol. 48: 543-52. PMID: 10583025
- CYP3A4-mediated hepatic metabolism of the HIV-1 protease inhibitor saquinavir in vitro. | Eagling, VA., et al. 2002. Xenobiotica. 32: 1-17. PMID: 11824416
- P-glycoprotein and MRP1 expression and reduced ritonavir and saquinavir accumulation in HIV-infected individuals. | Meaden, ER., et al. 2002. J Antimicrob Chemother. 50: 583-8. PMID: 12356805
- The use of sandwich-cultured rat hepatocytes to determine the intrinsic clearance of compounds with different extraction ratios: 7-ethoxycoumarin and warfarin. | Treijtel, N., et al. 2005. Drug Metab Dispos. 33: 1325-32. PMID: 15951450
- Effect of Methamphetamine on Spectral Binding, Ligand Docking and Metabolism of Anti-HIV Drugs with CYP3A4. | Nookala, AR., et al. 2016. PLoS One. 11: e0146529. PMID: 26741368
- Recombinant expression and characterization of novel P450s from Actinosynnema mirum. | Schmitz, LM., et al. 2021. Bioorg Med Chem. 42: 116241. PMID: 34139548
- Ultra-high pressure liquid chromatography coupled to travelling wave ion mobility-time of flight mass spectrometry for the screening of pharmaceutical metabolites in wastewater samples: Application to antiretrovirals. | Mosekiemang, TT., et al. 2021. J Chromatogr A. 1660: 462650. PMID: 34788673
- Recent Advances in Biocatalysis for Drug Synthesis. | Kinner, A., et al. 2022. Biomedicines. 10: PMID: 35625702
- Two‐step screening for identification of drug‐metabolizing bacterial cytochromes P450 with diversified selectivity. | Hilberath, Thomas, et al. 2020. ChemCatChem. 12.6: 1710-1719.
- Stability Indicating RP-UPLC Method for Impurity Profiling of Darunavir and Ritonavir in Fixed Dose Drug Combination Product. | Buch, Munish and Hasit Vaghani. 2024. Ind. J. Pharm. Edu. Res. 58.2s: s558-s565.
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HIV.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Hydroxy Ritonavir, 5 mg | sc-358250 | 5 mg | $265.00 |