Human Thymic Fibroblasts Antibody (TE7): sc-73603

Human Thymic Fibroblasts Antibody (TE7) is a mouse monoclonal IgG1 kappa light chain antibody that detects Human Thymic Fibroblasts by immunofluorescence (IF). Anti-Human Thymic Fibroblasts antibody (TE7) is available as a non-conjugated format. Fibroblasts, including those found in the thymus, are crucial for synthesizing and maintaining the extracellular matrix, which provides structural support to tissues and plays a vital role in wound healing. Human Thymic Fibroblasts (TE7) monoclonal antibody helps study proteins that contribute to the unique microenvironment of the thymus, facilitating the development and maturation of T cells, which are essential for the adaptive immune response. The thymic fibroblasts create a specialized niche that supports thymocyte differentiation through the secretion of various cytokines and extracellular matrix components. Additionally, fibroblasts exhibit a diverse morphology and are not confined to a specific attachment, allowing them to adapt to various tissue environments. Their ability to proliferate easily makes them a favored choice for cell culture in biological research, and the identification of fibroblast markers, such as the intermediate filament protein Vimentin, aids in distinguishing these cells and understanding their mesodermal origin.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Human Thymic Fibroblasts Antibody (TE7) References:

1. Expression, purification, and kinetic characterization of full-length human fibroblast activation protein.  |  Sun, S., et al. 2002. Protein Expr Purif. 24: 274-81. PMID: 11858723
2. Human fibroblast migration in three-dimensional collagen gel in response to noninvasive electrical stimulus. I. Characterization of induced three-dimensional cell movement.  |  Sun, S., et al. 2004. Tissue Eng. 10: 1548-57. PMID: 15588414
3. Molecular characterization of the cytotoxic mechanism of multiwall carbon nanotubes and nano-onions on human skin fibroblast.  |  Ding, L., et al. 2005. Nano Lett. 5: 2448-64. PMID: 16351195
4. Influence of myosin II activity on stiffness of fibroblast cells.  |  Schäfer, A. and Radmacher, M. 2005. Acta Biomater. 1: 273-80. PMID: 16701806
5. High-level expression of basic fibroblast growth factor in transgenic soybean seeds and characterization of its biological activity.  |  Ding, SH., et al. 2006. Biotechnol Lett. 28: 869-75. PMID: 16786271
6. Morphologies of fibroblast cells cultured on surfaces of PHB films implanted by hydroxyl ions.  |  Hou, T., et al. 2006. J Biomater Sci Polym Ed. 17: 735-46. PMID: 16909942
7. Characterization of fibroblast morphology on bioactive surfaces using vertical scanning interferometry.  |  Revell, CM., et al. 2006. Matrix Biol. 25: 523-33. PMID: 16962756
8. Free radical scavenging effect of Pu-erh tea extracts and their protective effect on oxidative damage in human fibroblast cells.  |  Jie, G., et al. 2006. J Agric Food Chem. 54: 8058-64. PMID: 17032009
9. Identification and characterization of a fibroblast marker: FSP1.  |  Strutz, F., et al. 1995. J Cell Biol. 130: 393-405. PMID: 7615639

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Human Thymic Fibroblasts Antibody (TE7) has 4 citations in a variety of scientific publications.

Primary antibodies like Anti-Human Thymic Fibroblasts Antibody (TE7) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Human Thymic Fibroblasts Antibody (TE7) Specifications

Alternate Product Name: Human Thymic Fibroblasts

Product Clone Name: TE7

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids:

Epitope Target: Human Thymic Fibroblasts

Epitope Species: human

Product Reactivity/Detection: thymomas and differential detection of medastinal tumors

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: IF

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 4 citations in various scientific publications

Available Conjugates/Forms for Human Thymic Fibroblasts Antibody (TE7): N/A