HTMT dimaleate CAS: 195867-54-0
MF: C19H25F3N4O•2C4H4O4
MW: 614.57
A mixed H1/H2 histamine agonist that is significantly more potent than histamine itself.

HTMT dimaleate (CAS 195867-54-0)

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Alternate Names: Histaminetrifluoromethyl toluidide dimaleate
Application: HTMT dimaleate is a mixed H1/H2 histamine agonist that is significantly more potent than histamine itself
CAS Number: 195867-54-0
Molecular Weight: 614.57
Molecular Formula: C19H25F3N4O•2C4H4O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

HTMT dimaleate is a mixed Histamine H1 Receptor and Histamine H2 Receptor agonist. This compound is 4x104 times more active than histamine in H2-mediated effects in natural suppressor cells. HTMT dimaleate increases intracellular Ca2+ and IP3 in lymphocytes through a binding site other than H1, H2 or H3.


References

1. Khan, M.M., et al. 1986. J. Immunol. 137: 308-314. PMID: 3011908
2. Khan, M.M., et al. 1987. J. Med. Chem. 30: 2115-2120. PMID: 2959777

Physical State :
Solid
Solubility :
Soluble in water (100 mM), and DMSO (100 mM).
Storage :
Desiccate at room temperature
Boiling Point :
922.2° C at 760 mmHg (Predicted)
Refractive Index :
n20D 1.54 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
45073433
SMILES :
CC(NCCC1=CN=CN1)CCCCC(=O)NC2=CC=C(C=C2)C(F)(F)F.C(=C\\C(=O)O)\\C(=O)O.C(=C\\C(=O)O)\\C(=O)O

Download SDS (MSDS)

Certificate of Analysis

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