HSV-1 gC Antibody (H633): sc-69800

HSV-1 gC Antibody (H633) is a mouse monoclonal IgG2b antibody that detects HSV-1 glycoprotein C by western blotting (WB) and immunofluorescence (IF). HSV-1 gC plays a crucial role in the virus′s ability to evade the host immune response; HSV-1 gC (H633) antibody binds to the complement component C3b, effectively inhibiting its function and protecting the virus from complement-mediated neutralization. This immune evasion is particularly important as HSV-1 gC persists in the host, leading to recurrent infections. Additionally, HSV-1 gC enhances the activity of coagulation Factor VIIa on the virus, which subsequently activates Factor X, further contributing to the virus′s pathogenicity. The ability of HSV-1 gC to modulate both immune and coagulation pathways underscores its significance in the viral life cycle and its potential as a target for therapeutic interventions. Anti-HSV-1 gC antibody (H633) serves as an invaluable tool for researchers studying the mechanisms of viral infection and immune evasion.

The preferred HSV-1 gC antibody is HSV-1 gC Antibody (T96): sc-51626.