HSV-1 Antibody (20.7.1): sc-57863

HSV-1 Antibody (20.7.1) is a mouse monoclonal IgG1 kappa light chain antibody that detects HSV-1 protein in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. HSV-1 (20.7.1) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. The herpes simplex virus type 1 (HSV-1) is primarily known for causing orofacial lesions, commonly referred to as cold sores, and is a member of the Herpesviridae family, characterized by its large double-stranded DNA genome and an icosahedral nucleocapsid enveloped in a lipid bilayer. One of the critical aspects of HSV-1 is its ability to establish latency in the host′s sensory neurons after the initial infection, which is crucial for understanding the virus′s lifecycle and potential reactivation events that can lead to recurrent disease. The latent phase allows HSV-1 to evade the host′s immune response, making viral persistence a significant factor in the population. Understanding the mechanisms of latency and reactivation is vital for developing therapeutic strategies and vaccines against HSV-1, highlighting the importance of research tools like anti-HSV-1 antibody (20.7.1) in studying this complex viral behavior.

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HSV-1 Antibody (20.7.1) References:

1. The latency-associated gene of herpes simplex virus type 1 (HSV-1) interferes with superinfection by HSV-1.  |  Mador, N., et al. 2002. J Neurovirol. 8 Suppl 2: 97-102. PMID: 12491159
2. Use of the herpes simplex viral genome to construct gene therapy vectors.  |  Burton, EA., et al. 2003. Methods Mol Med. 76: 1-31. PMID: 12526156
3. Overexpression of an epitope-tagged serotonin transporter in serotonin neurons of the dorsal raphe nucleus using a defective HSV-1 vector.  |  Ni, Y., et al. 2003. Behav Brain Res. 138: 133-43. PMID: 12527444
4. Subcellular localization of herpes simplex virus type 1 UL51 protein and role of palmitoylation in Golgi apparatus targeting.  |  Nozawa, N., et al. 2003. J Virol. 77: 3204-16. PMID: 12584344
5. Polyamine metabolism in cells infected with herpes simplex virus.  |  McCormick, FP. and Newton, AA. 1975. J Gen Virol. 27: 25-33. PMID: 167106
6. Comparison of herpes simplex virus isolates using a quantitative selection assay for transformation.  |  Rapp, F. and Buss, ER. Intervirology. 6: 72-82. PMID: 179966
7. Comparison of DNA polymerase activities induced by herpes simplex virus types 1 and 2.  |  Purifoy, DJ. Intervirology. 6: 356-66. PMID: 187552
8. Enhancing the HSV-1-mediated antitumor immune response by suppressing Bach1.  |  Pan, C., et al. 2022. Cell Mol Immunol. 19: 516-526. PMID: 34983952
9. The Dilemma of HSV-1 Oncolytic Virus Delivery: The Method Choice and Hurdles.  |  Tang, G., et al. 2023. Int J Mol Sci. 24: PMID: 36835091
10. The immunobiology of corneal HSV-1 infection and herpetic stromal keratitis.  |  Antony, F., et al. 2024. Clin Microbiol Rev. 37: e0000624. PMID: 39078136
11. Differential feulgen-deoxyribonucleic acid hydrolysis patterns of Herpes simplex virus type 1 and type 2 infected cells.  |  Trusal, LR., et al. 1975. J Histochem Cytochem. 23: 283-8. PMID: 47871
12. Seroepidemiology and control of genital herpes: the value of type specific antibodies to herpes simplex virus.  |  Slomka, MJ. 1996. Commun Dis Rep CDR Rev. 6: R41-5. PMID: 8820192

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-HSV-1 Antibody (20.7.1) has 1 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

HSV-1 Antibody (20.7.1) Specifications

Alternate Product Name: Herpes simplex virus 1

Product Clone Name: 20.7.1

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids:

Epitope Target: HSV-1

Epitope Species: Stoker strain of HSV-

Product Reactivity/Detection: HSV-1

Species Reactivity/Detection:

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P)

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for HSV-1 Antibody (20.7.1): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin