HSV-1 Antibody (014): sc-57862
- HSV-1 Antibody (014) is a mouse monoclonal IgG2, cited in 2 publications, provided at 100 µg/ml
- raised against whole herpes simplex virus type 1
- recommended for detection of HSV1 by IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for HSV-1 Antibody (014). This work is in progress.
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HSV-1 Antibody (014) is a mouse monoclonal IgG2 antibody that detects herpes simplex virus type 1 (HSV-1) with reactivity to human samples by immunofluorescence (IF). Anti-HSV-1 antibody (014) is an invaluable tool for researchers studying viral biology, pathogenesis, and potential therapeutic interventions. HSV-1 is a member of the herpesvirus family, primarily known for causing orofacial lesions or cold sores. HSV-1 possesses a large double-stranded DNA genome and features an icosahedral nucleocapsid enveloped in a lipid bilayer, crucial for host cell infection. The lipid envelope contains glycoproteins that play essential roles in viral attachment and host cell penetration, facilitating infection. Understanding HSV-1′s structural components is vital for developing targeted antiviral therapies and vaccines, as these glycoproteins serve as potential targets for neutralizing antibodies.
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HSV-1 Antibody (014) References:
- Nectin-1 and HVEM: cellular receptors for HSV-1 in skin. | Knebel-Mörsdorf, D. 2016. Oncotarget. 7: 19087-8. PMID: 27031306
- HSV-1 and Endogenous Retroviruses as Risk Factors in Demyelination. | Bello-Morales, R., et al. 2021. Int J Mol Sci. 22: PMID: 34072259
- T cell immunity in HSV-1- and VZV-infected neural ganglia. | Boeren, M., et al. 2023. Trends Microbiol. 31: 51-61. PMID: 35987880
- Role of Heparanase and Syndecan-1 in HSV-1 Release from Infected Cells. | Sharma, P., et al. 2022. Viruses. 14: PMID: 36298711
- Stacking the odds: Multiple sites for HSV-1 latency. | Wang, S., et al. 2023. Sci Adv. 9: eadf4904. PMID: 36696497
- Role of IL-27 in HSV-1-Induced Herpetic Stromal Keratitis. | Antony, F., et al. 2023. J Immunol. 211: 474-485. PMID: 37326494
- Noncanonical autophagy is a new strategy to inhibit HSV-1 through STING1 activation. | Zheng, Z., et al. 2023. Autophagy. 19: 3096-3112. PMID: 37471002
- HSV-1 exploits host heterochromatin for nuclear egress. | Lewis, HC., et al. 2023. J Cell Biol. 222: PMID: 37516914
- HSV-1 employs UL56 to antagonize expression and function of cGAMP channels. | Blest, HTW., et al. 2024. Cell Rep. 43: 114122. PMID: 38652659
- The HSV-1 pUL37 protein promotes cell invasion by regulating the kinesin-1 motor. | Kim, D., et al. 2024. Proc Natl Acad Sci U S A. 121: e2401341121. PMID: 38696466
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HSV-1 Antibody (014) | sc-57862 | 100 µg/ml | $316.00 |