HSV-1/2 gE Envelope Protein Antibody (0112): sc-58153

HSV-1/2 gE Envelope Protein Antibody (0112) is a mouse monoclonal IgG2a antibody that detects HSV-1/2 gE Envelope Protein of Herpes simplex virus 1 origin by immunofluorescence (IF). HSV-1/2 gE Envelope Protein (0112) antibody is available as the non-conjugated anti-HSV-1/2 gE Envelope Protein antibody. Glycoprotein E (gE) plays a crucial role in herpes simplex virus pathogenesis by facilitating viral entry into host cells and immune response evasion. gE enables viral envelope fusion with host cell membranes, allowing viral genome entry and infection initiation. This function aids in establishing infection and promotes virus spread between cells and tissues, resulting in characteristic herpes infection symptoms. Understanding gE′s role in viral entry and immune evasion helps develop targeted therapies and vaccines against herpes simplex virus infections. Anti-HSV-1/2 gE Envelope Protein antibody (0112) serves as a valuable research tool for studying herpes simplex virus biology and host cell interactions.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

HSV-1/2 gE Envelope Protein Antibody (0112) References:

1. Prevention of the interaction between HVEM, herpes virus entry mediator, and gD, HSV envelope protein, by a Keggin polyoxotungstate, PM-19.  |  Dan, K. and Yamase, T. 2006. Biomed Pharmacother. 60: 169-73. PMID: 16675194
2. Herpes simplex virus type 2 (HSV-2) infection in women attending an antenatal clinic in the South Pacific island nation of Vanuatu.  |  Haddow, LJ., et al. 2007. Sex Transm Dis. 34: 258-61. PMID: 16940899
3. The microenvironment of vulvar skin in women with symptomatic and asymptomatic herpes simplex virus type 2 (HSV-2) infection.  |  Löwhagen, GB., et al. 2006. J Eur Acad Dermatol Venereol. 20: 1086-9. PMID: 16987263
4. Development and validation of a capillary electrophoresis method for the characterization of herpes simplex virus type 1 (HSV-1) thymidine kinase substrates and inhibitors.  |  Iqbal, J., et al. 2007. J Chromatogr B Analyt Technol Biomed Life Sci. 846: 281-90. PMID: 17023224
5. The HSV-2 protein ICP10PK prevents neuronal apoptosis and loss of function in an in vivo model of neurodegeneration associated with glutamate excitotoxicity.  |  Golembewski, EK., et al. 2007. Exp Neurol. 203: 381-93. PMID: 17046754
6. Association between HSV-2 and HIV-1 viral load in semen, cervico-vaginal secretions and genital ulcers of Thai men and women.  |  Chu, K., et al. 2006. Int J STD AIDS. 17: 681-6. PMID: 17059638
7. HSV infection and immunosuppression.  |  Sindhi, R. 2006. Liver Transpl. 12: 1906-7. PMID: 17133569
8. Sulfasalazine unveils a contact-independent HSV-TK/ganciclovir gene therapy bystander effect in malignant gliomas.  |  Robe, PA., et al. 2007. Int J Oncol. 30: 283-90. PMID: 17143539
9. Herpes simplex virus type 2 (HSV-2) establishes latent infection in a different population of ganglionic neurons than HSV-1: role of latency-associated transcripts.  |  Margolis, TP., et al. 2007. J Virol. 81: 1872-8. PMID: 17151134
10. HSV-2- and HIV-1- permissive cell lines co-infected by HSV-2 and HIV-1 co-replicate HSV-2 and HIV-1 without production of HSV-2/HIV-1 pseudotype particles.  |  Legoff, J., et al. 2007. Virol J. 4: 2. PMID: 17207276
11. Simultaneous tracking of capsid, tegument, and envelope protein localization in living cells infected with triply fluorescent herpes simplex virus 1.  |  Sugimoto, K., et al. 2008. J Virol. 82: 5198-211. PMID: 18353954
12. Enhancement of HSV-1 cell-free virion release by the envelope protein gC.  |  Frost, TC., et al. 2024. Virology. 596: 110120. PMID: 38805801

The preferred HSV-1 antibody is HSV-1 Antibody (20.7.1): sc-57863.