HSPA14 Antibody (G-9): sc-398208
- HSPA14 Antibody (G-9) is a mouse monoclonal IgG1 κ HSPA14 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 280-307 within an internal region of HSPA14 of human origin
- HSPA14 Antibody (G-9) is recommended for detection of HSPA14 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- Anti-HSPA14 Antibody (G-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for HSPA14 Antibody (G-9) for WB applications. These reagents are now offered in bundles with HSPA14 Antibody (G-9) (see ordering information below).
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HSPA14 Antibody (G-9) is a mouse monoclonal IgG1 kappa light chain antibody that detects HSPA14 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HSPA14 (G-9) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. HSPA14 protein, also known as heat shock 70kDa protein 14, HSP70-4, or HSP70L1, consists of 509 amino acids and is derived from human dendritic cells. HSPA14 plays a crucial role in dendritic cell maturation, which is essential for initiating and regulating immune responses. HSPA14 stimulates the secretion of proinflammatory cytokines such as interleukin 12p70, interleukin 1β, and tumor necrosis factor alpha, as well as chemokines like IP-10, MIP-1α, MIP-1β, and RANTES. These interactions are vital for the immune system′s ability to respond to pathogens and maintain homeostasis. Anti-HSPA14 antibody (G-9) serves as an invaluable tool for researchers studying immune responses and the role of heat shock proteins in cellular processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
HSPA14 Antibody (G-9) References:
- Polymorphic analysis of the three MHC-linked HSP70 genes. | Milner, CM. and Campbell, RD. 1992. Immunogenetics. 36: 357-62. PMID: 1356099
- Novel heat shock protein Hsp70L1 activates dendritic cells and acts as a Th1 polarizing adjuvant. | Wan, T., et al. 2004. Blood. 103: 1747-54. PMID: 14592822
- Hsp70-like protein 1 fusion protein enhances induction of carcinoembryonic antigen-specific CD8+ CTL response by dendritic cell vaccine. | Wu, Y., et al. 2005. Cancer Res. 65: 4947-54. PMID: 15930317
- The chaperones MPP11 and Hsp70L1 form the mammalian ribosome-associated complex. | Otto, H., et al. 2005. Proc Natl Acad Sci U S A. 102: 10064-9. PMID: 16002468
- Structure and expression of the three MHC-linked HSP70 genes. | Milner, CM. and Campbell, RD. 1990. Immunogenetics. 32: 242-51. PMID: 1700760
- Protective effect of a RSV subunit vaccine candidate G1F/M2 was enhanced by a HSP70-Like protein in mice. | Zeng, R., et al. 2008. Biochem Biophys Res Commun. 377: 495-499. PMID: 18851947
- The human heat-shock protein family. Expression of a novel heat-inducible HSP70 (HSP70B') and isolation of its cDNA and genomic DNA. | Leung, TK., et al. 1990. Biochem J. 267: 125-32. PMID: 2327978
- Isolation and functional analysis of a human 70,000-dalton heat shock protein gene segment. | Voellmy, R., et al. 1985. Proc Natl Acad Sci U S A. 82: 4949-53. PMID: 3927293
- Genomic structure of the spermatid-specific hsp70 homolog gene located in the class III region of the major histocompatibility complex of mouse and man. | Ito, Y., et al. 1998. J Biochem. 124: 347-53. PMID: 9685725
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HSPA14 Antibody (G-9) | sc-398208 | 200 µg/ml | $322.00 | |||
HSPA14 Antibody (G-9): m-IgG Fc BP-HRP Bundle | sc-527750 | 200 µg Ab; 10 µg BP | $361.00 | |||
HSPA14 Antibody (G-9): m-IgG1 BP-HRP Bundle | sc-533123 | 200 µg Ab; 20 µg BP | $361.00 | |||
HSPA14 Antibody (G-9) AC | sc-398208 AC | 500 µg/ml, 25% agarose | $424.00 | |||
HSPA14 Antibody (G-9) HRP | sc-398208 HRP | 200 µg/ml | $322.00 | |||
HSPA14 Antibody (G-9) FITC | sc-398208 FITC | 200 µg/ml | $336.00 | |||
HSPA14 Antibody (G-9) PE | sc-398208 PE | 200 µg/ml | $349.00 | |||
HSPA14 Antibody (G-9) Alexa Fluor® 488 | sc-398208 AF488 | 200 µg/ml | $364.00 | |||
HSPA14 Antibody (G-9) Alexa Fluor® 546 | sc-398208 AF546 | 200 µg/ml | $364.00 | |||
HSPA14 Antibody (G-9) Alexa Fluor® 594 | sc-398208 AF594 | 200 µg/ml | $364.00 | |||
HSPA14 Antibody (G-9) Alexa Fluor® 647 | sc-398208 AF647 | 200 µg/ml | $364.00 | |||
HSPA14 Antibody (G-9) Alexa Fluor® 680 | sc-398208 AF680 | 200 µg/ml | $364.00 | |||
HSPA14 Antibody (G-9) Alexa Fluor® 790 | sc-398208 AF790 | 200 µg/ml | $364.00 | |||
HSPA14 (G-9) Neutralizing Peptide | sc-398208 P | 100 µg/0.5 ml | $69.00 |