HoxC9 Antibody (HOXCA6E6): sc-81100

HoxC9 Antibody (HOXCA6E6) is a mouse monoclonal IgG2b antibody that detects HoxC9 protein of human origin by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-HoxC9 antibody (HOXCA6E6) is available as a non-conjugated format. Hox proteins, including HoxC9, are critical transcription factors that orchestrate developmental processes and cellular differentiation by regulating downstream target gene expression. HoxC9 is integral to establishing positional identities along the anterior-posterior body axis, influencing morphologic features of various tissues. HoxC9 spans 260 amino acids and contains a homeobox DNA-binding domain, essential for gene regulation function. HoxC9 expression in esophageal cancer cells suggests a potential role in tumorigenesis and cancer progression. Understanding HoxC9 interactions with various transcriptional co-factors is vital for elucidating functions in both normal development and disease states. HoxC9′s ability to modulate gene expression highlights importance in developmental biology and potential as a therapeutic target in cancer research.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

HoxC9 Antibody (HOXCA6E6) References:

1. Expression of homeobox-containing genes in cDNA libraries derived from cattle oocytes and preimplantation stage embryo.  |  Ponsuksili, S., et al. 2001. Mol Reprod Dev. 60: 297-301. PMID: 11599040
2. cDNA cloning and expression of the human NOBOX gene in oocytes and ovarian follicles.  |  Huntriss, J., et al. 2006. Mol Hum Reprod. 12: 283-9. PMID: 16597639
3. A subgroup of HOX Abd-B gene is differentially expressed in cervical cancer.  |  López, R., et al. 2006. Int J Gynecol Cancer. 16: 1289-96. PMID: 16803519
4. Expression of HOXC9 and E2F2 are up-regulated in CD133(+) cells isolated from human astrocytomas and associate with transformation of human astrocytes.  |  Okamoto, OK., et al. 2007. Biochim Biophys Acta. 1769: 437-42. PMID: 17588684
5. [Expression of 39 HOX genes in esophageal cancer cell lines].  |  Gu, ZD., et al. 2007. Zhonghua Wei Chang Wai Ke Za Zhi. 10: 365-7. PMID: 17659465
6. Expression of AbdB-type homeobox genes in human tumors.  |  Redline, RW., et al. 1994. Lab Invest. 71: 663-70. PMID: 7967520
7. Restricted expression of homeobox genes distinguishes fetal from adult human smooth muscle cells.  |  Miano, JM., et al. 1996. Proc Natl Acad Sci U S A. 93: 900-5. PMID: 8570656

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-HoxC9 Antibody (HOXCA6E6) has 3 citations in a variety of scientific publications.

Primary antibodies like Anti-HoxC9 Antibody (HOXCA6E6) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

HoxC9 Antibody (HOXCA6E6) Specifications

Alternate Product Name: HoxC9

Product Clone Name: HOXCA6E6

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b

Amino Acids:

Epitope Target: HoxC9

Epitope Species: human

Product Reactivity/Detection: HoxC9

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF

Vialing Information: Each vial contains 100 µg IgG_2b in 1.0 ml of PBS with < 0.1% sodium azide and 1.0% stabilizer protein

Research Citations: 3 citations in various scientific publications

Available Conjugates/Forms for HoxC9 Antibody (HOXCA6E6): N/A